Tuneable nanochannel formation for sample-in/answer-out devices.

Chem Commun (Camb)

Australian Centre for Research on Separation Science, School of Chemistry, University of Tasmania, Private Bag 75, Hobart, Tasmania 7001, Australia.

Published: April 2013

Control of the dielectric breakdown of PDMS was achieved by limiting the current during the breakdown process. This enabled tuning of the nanochannel pore size and hence their permeability for molecules of different molecular weights. This method enabled the analysis of the drug quinine from whole blood in 3 min using a simple, disposable microfluidic device.

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Source
http://dx.doi.org/10.1039/c3cc38330jDOI Listing

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