AI Article Synopsis
- Hyper-reactive malarial splenomegaly (HMS) is characterized by major splenomegaly, elevated IgM and antimalarial antibodies, and a positive response to treatment.
- Although malaria is widespread in Pakistan, cases of HMS are rare.
- This report discusses a patient with large spleen size and malaria infection, noting the inconsistency with typical HMS diagnostic criteria and providing a brief overview of HMS.
Article Abstract
Hyper-reactive malarial splenomegaly (HMS) is diagnosed by the presence of massive splenomegaly, raised IgM and antimalarial antibodies and a response to antimalarial therapy. Although malaria is endemic to Pakistan, HMS is uncommon. We report on HMS in a patient with massive splenomegaly, positive Plasmodium falciparum polymerase chain reaction but normal immunoglobulin M antibody levels. The investigations were not consistent with any other diagnosis. HMS is also briefly reviewed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/0049475512473602 | DOI Listing |
Publication Analysis
Top Keywords
hyper-reactive malarial
8
malarial splenomegaly
8
raised igm
8
massive splenomegaly
8
splenomegaly
4
splenomegaly absence
4
absence raised
4
igm antibodies
4
antibodies hyper-reactive
4
hms
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!