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Awareness and Knowledge of Endocrine-Disrupting Chemicals Among Pregnant Women and New Mothers: A Cross-Sectional Survey Study.
Toxics
December 2024
Department of Social Pediatrics, Institute of Child Health, Hacettepe University, Ankara 06230, Türkiye.
Background/objectives: Endocrine-disrupting chemicals (EDCs) are exogenous substances that interfere with hormone regulation, leading to adverse health outcomes. Despite the wide use of EDCs in daily products like plastics, personal care items, and food packaging, public awareness remains low. Pregnant women and new mothers are particularly vulnerable, as exposure to EDCs during early life stages can have long-term health impacts.
View Article and Find Full Text PDFOxidative Stress and Keap1-Nrf2 Pathway Involvement in Bisphenol A-Induced Liver Damage in Rats.
Toxics
November 2024
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Bisphenol A (BPA), extensively utilized in the manufacture of epoxy resins and polycarbonate plastics, is prevalent in the environment. Its exposure has been associated with an increased risk of hepatic lesions; however, the underlying mechanisms and the spectrum of its effects remain poorly understood. This study investigates the role of the Keap1-Nrf2 signaling pathway in regulating BPA-induced hepatotoxicity in vivo using a rat model.
View Article and Find Full Text PDFA Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold Nanoparticles.
Micromachines (Basel)
December 2024
Institute of UTINAM, UMR-CNRS 6213, University of Franche-Comté, 16 Gray Road, 25030 Besançon, France.
Bisphenol A (BPA) is a commonly synthetic chemical mainly used in producing plastic items. It is an endocrine-disrupting compound that causes irreversible health and environmental damage. Developing a simple method for BPA effective quantitative monitoring is emergently necessary.
View Article and Find Full Text PDFBisphenol A and Its Emergent Substitutes: State of the Art of the Impact of These Plasticizers on Oxidative Stress and Its Role in Vascular Dysfunction.
Antioxidants (Basel)
November 2024
Department of Toxicology, Center for Research and Advanced Studies of the National Polytechnic Institute, Mexico City 07360, Mexico.
The "One Health approach" has evidenced the significant impact of xenobiotic exposure to health, and humans are a relevant target for their toxic effects. Bisphenol A (BPA) exerts a ubiquitous exposure source in all ecosystems. Given its endocrine-disrupting and harmful consequences on health, several countries have enforced new regulations to reduce exposure to BPA.
View Article and Find Full Text PDFCoating Agents for Resin Composites: Effect on Color Stability, Roughness, and Surface Micromorphology Subjected to Brushing Wear.
Oper Dent
January 2025
*Roberta Tarkany Basting, DDS, MSc, PhD, Professor, Restorative Dentistry Department, Faculdade São Leopoldo Mandic, São Paulo, Brazil.
This study evaluated the influence of six resin composite coating agents on color stability and surface roughness after toothbrushing abrasion. Discs (Ø6 mm x 2 mm) of nanofilled resin composite (Filtek Z350XT) were prepared for application of coating agents (n=10): control (absence), two surface sealants (PermaSeal and BisCover LV), two adhesive systems (Scotchbond Multi-Purpose Adhesive/3M Oral Care and Single Bond Universal), and two modeling liquids (Modeling Resin and Composite Wetting Resin). CIELab*, WID, and color change (ΔEab, ΔE00, and ΔWID) were analyzed at baseline, after finishing and polishing, after application of coating agents, after coffee staining (simulating 30 days and one year of staining), and after toothbrushing abrasion.
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