AI Article Synopsis
- The study compared anesthesia and recovery effects of propofol and methohexital during a short procedure for pregnancy termination, assessing psychomotor performance with tests.
- More muscle movements and hiccups were reported with methohexital, but both anesthetics showed no significant differences in pain or apnea after injection.
- While recovery was quicker with methohexital at 15 minutes, propofol provided better psychomotor performance after one hour, indicating its smoother induction as a possible advantage.
Article Abstract
Anesthesia and recovery during the first hour after propofol and methohexital anesthesia for termination of pregnancy, lasting about 12 min, were compared, the latter in a double-blind manner by means of psychomotor tests (coin counting and continuous auditory reaction time). Muscle movements and hiccups were seen significantly more frequently during methohexital inductions. No differences were seen regarding pain at the site of injection or apnea between the groups. At 15 min after the last dose of anesthetic, recovery after methohexital was ahead of that after propofol, but after 1 h, psychomotor performance was better in the propofol group. Side-effects during recovery were few, and incidences did not differ significantly. Although the difference in reaction time test was significant, it was hardly large enough to be of any clinical importance. Both drugs are useful for brief outpatient anesthesia, but smoother induction gives propofol an edge over methohexital.
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| http://dx.doi.org/10.1111/j.1399-6576.1990.tb03072.x | DOI Listing |
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