Background: Human babesiosis is a rare tick-borne infectious disease. The clinical presentation ranges from an asymptomatic form to a life threatening infection with severe hemolysis. Human babesiosis due to Babesia microti is the most common and is endemic in North America.

Case Presentation: We report a European patient with severe pancytopenia and reactive hemophagocytosis related to a Babesia microti infection. Babesia infection was acquired during a travel in the USA.

Conclusion: Babesiosis should be considered in patients who traveled in endemic areas, especially North America for the most common agent Babesia microti.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598249PMC
http://dx.doi.org/10.1186/1471-2334-13-99DOI Listing

Publication Analysis

Top Keywords

babesia microti
16
human babesiosis
8
babesia
5
microti unusual
4
unusual travel-related
4
travel-related disease
4
disease background
4
background human
4
babesiosis rare
4
rare tick-borne
4

Similar Publications

Background: Babesiosis poses significant risks of adverse outcomes in individuals with immunocompromising conditions (IC) and asplenia/hyposplenia (AH). This study compares clinical outcomes between these vulnerable groups and immunocompetent patients.

Methods: A multicenter retrospective cohort study included adult patients with laboratory-confirmed babesiosis from 2009 to 2023.

View Article and Find Full Text PDF

A novel genotype of Babesia microti-like group in Ixodes montoyanus ticks parasitizing the Andean bear (Tremarctos ornatus) in Ecuador.

Exp Appl Acarol

January 2025

Laboratorio de Vectores y Enfermedades Transmitidas, Departamento de Ciencias Biológicas, CENUR Litoral Norte, Universidad de la República, Salto, Uruguay.

Babesia species (Piroplasmida) are hemoparasites that infect erythrocytes of mammals and birds and are mainly transmitted by hard ticks (Acari: Ixodidae). These hemoparasites are known to be the second most common parasites infecting mammals, after trypanosomes, and some species may cause malaria-like disease in humans. Diagnosis and understanding of Babesia diversity increasingly rely on genetic data obtained through molecular techniques.

View Article and Find Full Text PDF

Small mammals as hosts of vector-borne pathogens in the High Tatra Mountains region in Slovakia, Central Europe.

Curr Res Parasitol Vector Borne Dis

December 2024

Research Station and Museum of the Tatra National Park, Tatranská Lomnica, 059 60, Slovakia.

Rodents and insectivores are significant reservoirs of many zoonotic pathogens, contributing to the transmission of diseases affecting human and animal health. This study investigated the prevalence and diversity of vector-borne pathogens in small mammals within the High Tatras region of Slovakia, an area with substantial recreational activity and protected zones. A total of 156 small mammals, comprising ten species, were screened for pathogens such as spp.

View Article and Find Full Text PDF

Proteomic Identification and Functional Analysis of Reveals Heparin-Binding Proteins.

J Trop Med

January 2025

National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Laboratory of Parasite and Vector Biology, Ministry of Public Health, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Shanghai 200025, China.

Glycosaminoglycan (GAG) molecules on the surface of red blood cells play an important regulatory role in the invasion of merozoites of apicomplexan protozoa. Heparan sulfate, a type of GAG molecule, has been identified as an important receptor facilitating the invasion of red blood cells by these parasites. Proteins in the parasite that exhibit strong affinity for heparin may play a pivotal role in this invasion process.

View Article and Find Full Text PDF

With climate and land use changes, tick-borne pathogens are expected to become more widely distributed in Canada. Pathogen spread and transmission in this region is modulated by changes in the abundance and distribution of tick and host populations. Here, we assessed the relationships between pathogens detected in and mammal hosts at sites of different levels of disease risk using data from summer field surveys in Ontario and Quebec, Canada.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!