Phenolic endocrine disrupting chemicals are environmental pollutants with xenostrogen effects in wildlife and humans. The aim of this study was to determine 4-nonylphenol, Octylphenol, and Bisphenol A residues in various tissues of carp fish samples from Anzali wetland, Iran. 4-NP, OP, and BPA were detected with GC-MS in the muscle of fish from sampling location with maximal concentrations of 8.17, 9.67 and 5.87 μg/gdw, respectively. The highest concentrations of these compounds were found in the liver by HPLC. Since many endocrine disrupting substances were significantly lipophilic, distributing of these compounds into fish tissue has been correlated with lipid content.
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http://dx.doi.org/10.1007/s00128-013-0964-0 | DOI Listing |
Int J Mol Sci
December 2024
Department of Chemistry and Biology, University of Salerno, 84084 Fisciano, Italy.
Alkylphenols are byproducts of anthropogenic activities that widely contaminate waters, soils and air; among them, the most represented are 4-nonylphenol (4-NP) and 4-octylphenol (4-OP). These compounds tend to bioaccumulate in animal and plant tissues and also represent a risk to human health. Indeed, humans are constantly exposed to alkylphenols through ingestion of contaminated water and food, inhalation and dermal absorption.
View Article and Find Full Text PDFEnviron Res
January 2025
Laboratory of Environmental Aquatic Chemistry, Department of Environmental Science, Shaanxi Normal University, Xi'an, 710062, PR China. Electronic address:
With the rapid progression of industrialization, the application and release of endocrine disruptors (EDCs), including bisphenol A (BPA), octylphenol and nonylphenol have significantly increased, presenting substantial health hazards. Conventional analytical techniques, such as high-performance liquid chromatography and gas chromatography-mass spectrometry, are highly sophisticated but suffer from complex procedures and high costs. To overcome these limitations, this study introduces an innovative spectral methodology for the simultaneous detection of multiple aquatic multicomponent EDCs.
View Article and Find Full Text PDFEnviron Pollut
December 2024
State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, Beijing, 100875, China.
This study investigated geospatial distributions of endocrine-disrupting chemicals (EDCs) in the waters of the Dongjiang River and their associations with anthropogenic activities. Fifteen EDCs, with total concentrations in the river water of 149-2525 ng/L were detected, with bisphenol-A, 4-nonylphenol, 4-tert-octylphenol, p-hydroxybenzoic acid, and methylparaben being the five predominant EDCs. The total estrogen concentration was high downstream and significantly correlated with the spatial distribution of urban land use, wastewater discharge, population, and gross domestic product, indicating human activities have increased estrogen levels and threatened ecological health.
View Article and Find Full Text PDFEnviron Pollut
November 2024
The South Kyushu Okinawa Unit Center, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan; Department of Public Health, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
Background: Alkylphenols can originate from numerous products containing alkylphenol ethoxylates, including cleaning products, household items, and cosmetics. Some phenols, such as nonylphenol, are known to be endocrine disruptors, and exposure to them is thought to have contributed to the recent increase in allergic diseases such as asthma. However, the impacts of prenatal phenol exposure on asthma development in children are still unclear.
View Article and Find Full Text PDFEcotoxicol Environ Saf
September 2024
Department of Sanitary Chemistry, School of Public Health, Guangxi Medical University, Nanning, Guangxi 530021, China; Guangxi Key Laboratory of Environment and Health Research, Guangxi Medical University, Nanning, Guangxi 530021, China. Electronic address:
The liver toxicity of alkylphenols (APs) has been demonstrated in animal studies. However, relevant epidemiological evidence is still lacking in humans, especially during pregnancy. We obtained the levels of biochemical indicators of liver function in early (<13 weeks, mean gestation=9.
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