Purpose: The aim of this study was to establish the value of magnetic resonance angiography (MRA) in diagnosing) Swyer-James syndrome (SJS) and to compare MRA and ventilation-perfusion (V/Q) scan results in patients with established SJS.
Methods: The V/Q scans and the MRA findings of 22 lungs of 11 patients with SJS (6 males, 5 females; age range: 17-69 years, mean: 38.4 years) were retrospectively studied. The perfusion scan was performed after the injection of Tc macroaggregated albumin. After 2 days, the ventilation scan was performed by using Tc diethylene triamine penta-acetic acid aerosol. The MRA was performed with a 1.5 T magnetic resonance unit. We compared the MRA and V/Q scan findings of the lungs of the patients.
Results: The V/Q scans showed the characteristic pattern of a matched V/Q defect on the affected lungs. The MRA displayed a smaller pulmonary artery and markedly poor peripheral vasculature on the affected side in all patients. The MRA had a sensitivity of 84.6%, a specificity of 100% for the detection SJS. Interobserver variability was minimum as indicated by a weighted kappa statistic of 0.818.
Conclusion: This study indicates that the MRA is a fast, accurate, without radiation, and noninvasive technique for supporting the diagnosis of SJS. But, V/Q scans showed additional segmental perfusion/ventilation abnormalities on contralateral lung to reveal the segmental involvement of SJS. As a result, the MRA has no more any extra advantages for patient management.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/RLU.0b013e3181d624dd | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Ventilation/Perfusion Mismatch in Pulmonary Vein Stenosis Secondary to Atrial Fibrillation Ablation.
Asia Ocean J Nucl Med Biol
January 2025
Department of Radiology, Tokushima University Hospital, Tokushima City, Japan.
Article Synopsis
- Two patients with paroxysmal atrial fibrillation developed pulmonary vein stenosis (PVS) after AF ablation, with Case 1 being a female in her 50s and Case 2 a male in his 60s.
- The first patient showed high-degree left superior PVS 15 months post-ablation, while the second had progressive PVS nine months later, confirmed through contrast-enhanced CT and ventilation-perfusion scans.
- PVS is a rare complication of AF ablation that can lead to severe issues if untreated, and the case report emphasizes the importance of V/Q scans in assessing PVS despite its common association with pulmonary embolism evaluations.
How necessary it is to perform a ventilation scan in patients with a history of COVID-19 to rule out pulmonary thromboembolism?
Asia Ocean J Nucl Med Biol
January 2025
Nuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Objectives: This study evaluated the necessity of a ventilation scan in patients suspected of PE with a history of COVID-19 infection.
Methods: This was a cross-sectional study of patients with PCR-confirmed COVID-19 and suspected PE at a tertiary care hospital in 2020. They underwent ventilation/perfusion (V/Q) scintigraphy using single-photon emission computed tomography/computed tomography (SPECT/CT) and CT scans with or without contrast.
Development and validation of a Prediction Model for Chronic Thromboembolic Pulmonary Disease.
Respir Res
December 2024
Department of Respiratory and Critical Care Medicine, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 9677 Jing Shi Road, Jinan, 250000, Shandong, China.
Background: Acute pulmonary embolism (APE) is a critical disease with a high mortality rate, some of the surviving patients may develop chronic thromboembolic pulmonary disease (CTEPD), which affects the patient's prognosis. However, the research on the early diagnosis of CTEPD is limited. This study aimed to establish a prediction model for earlier identification of CTEPD.
View Article and Find Full Text PDFComparison of ventilation/perfusion scintigraphy and pulmonary CT angiography: Findings in the diagnosis of CTEPH and CTED.
Hell J Nucl Med
December 2024
Department of Nuclear Medicine, Abant Izzet Baysal University, Bolu, Turkey.
Objective: Despite the high sensitivity and specificity of ventilation/perfusion (VQ) scintigraphy in the diagnosis of chronic thromboembolic pulmonary hypertension (CTEPH) and chronic thromboembolic disease (CTED), V/Q scintigraphy cannot distinguish whether the thrombus is acute or chronic. In our study, we aimed to compare pulmonary computed tomography angiography (CTA) findings with V/Q scintigraphy findings in CTEPH and CTED patients and to identify findings that would indicate chronic thrombus.
Subjects And Methods: Eighteen patients diagnosed with CTEPH and CTED at our institution were included in the study between January 2020 and January 2024.
Pathophysiological Markers of Acute Respiratory Distress Syndrome Severity Are Correlated With Ventilation-Perfusion Mismatch Measured by Electrical Impedance Tomography.
Crit Care Med
January 2025
Department of Anesthesia, Critical Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Objectives: Pulmonary ventilation/perfusion (V/Q) mismatch measured by electrical impedance tomography (EIT) is associated with the outcome of patients with the acute respiratory distress syndrome (ARDS), but the underlying pathophysiological mechanisms have not been fully elucidated. The present study aimed to verify the correlation between relevant pathophysiological markers of ARDS severity and V/Q mismatch.
Design: Prospective observational study.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!