Boolean relations, such as and, or, and not, are a fundamental way to create new concepts out of old. Classic psychological studies showed that such concepts differed in how difficult they were to learn, but did not explain the source of these differences. Recent theories have reinvigorated the field with explanations ranging from the complexity of minimal descriptions of a concept to the relative invariance of its different instances. We review these theories and argue that the simplest explanation - the number of mental models required to represent a concept - provides a powerful account. However, no existing theory explains the process in full, such as how individuals spontaneously describe concepts.
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http://dx.doi.org/10.1016/j.tics.2013.01.007 | DOI Listing |
NPJ Syst Biol Appl
September 2024
Instituto de Ecología, Universidad Nacional Autónoma de México, Ciudad de México, México.
In several carcinomas, including hepatocellular carcinoma, it has been demonstrated that cancer stem cells (CSCs) have enhanced invasiveness and therapy resistance compared to differentiated cancer cells. Mathematical-computational tools could be valuable for integrating experimental results and understanding the phenotypic plasticity mechanisms for CSCs emergence. Based on the literature review, we constructed a Boolean model that recovers eight stable states (attractors) corresponding to the gene expression profile of hepatocytes and mesenchymal cells in senescent, quiescent, proliferative, and stem-like states.
View Article and Find Full Text PDFJ Craniofac Surg
August 2024
Center for Cleft Lip and Palate Treatment, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Currently, there remain unresolved issues in the treatment of alveolar clefts, the resolution of which could greatly benefit many patients with cleft lip and palate. In alveolar cleft treatment research, a reliable tool for pre- and postoperative assessment is crucial. This study presents a concise and accurate method for postoperative evaluations of alveolar treatment, which can rapidly and accurately obtain the shape and volume of the newly formed bone.
View Article and Find Full Text PDFItal J Dermatol Venerol
October 2024
Department of Medical Sciences, Clinic of Dermatology, University of Turin, Turin, Italy -
ACS Nano
July 2024
State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Simultaneous detection and structural characterization of protein variants on a single platform are highly desirable but technically challenging. Herein, we present a single-molecule spectral system based on a gold plasmonic nanopore for analyzing two peptides and their single-point mutated variants. The gold plasmonic nanopore enabled the high-throughput acquisition of surface-enhanced Raman scattering (SERS) spectra at the single-molecule level by electrically driving analytes into hot spots.
View Article and Find Full Text PDFMed J Islam Repub Iran
March 2024
Department of Medical Library and Information Science, School of Allied Medical Sciences, Abadan University of Medical Sciences, Abadan, Iran.
Background: The present study was motivated by issues with earlier studies on documenting knowledge and experiences. This scoping review investigates and maps the procedures for documenting organizational knowledge and experiences.
Methods: Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) extension for Scoping Reviews (PRISMA-ScR) guidelines, a scoping review was conducted.
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