APAM was prepared under the action of composite initiator and UV irradiation, using acryl amide (AM), 2-acrylamido-2-methyl propane sulfonic acid (AMPS) and acrylic acid (AA) as raw materials. The paper studied the effect of proportion between monomers, monomer ratio, initiator concentration and other factors on intrinsic viscosity of the polymer, and optimized preparation conditions. The chemical structure and thermal stability of APAM were characterized by UV, FTIR, SEM and DTA-TGA respectively. The results showed that the APAM with the intrinsic viscosity 1.6 x 10(3) mL x g(-1) can prepared when the proportion between monomers was 70 : 10 : 10, the monomer ratio was 40%, initiator concentration was 0.20%, pH was 9 and the illumination time was 60 min.
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Int Immunopharmacol
December 2024
Department of Traditional Chinese Medicine, The Changhai Hospital, Naval Military Medical University, Shanghai, China. Electronic address:
Ginsenoside Rg3 is an extract from ginseng and has the activities of antitumor in a variety of carcinomas, making it a promising monomer of Chinese herbal medicine for tumor treatment. This study aimed to investigate the targets and mechanisms of action of Rg3 in hepatocellular carcinoma (HCC). The molecular structure of Rg3 was obtained, and 100 potential targets were identified using the SwissTargetPrediction database.
View Article and Find Full Text PDFJ Phys Chem B
November 2024
National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 2, Umezono 1-1-1, Tsukuba 305-8568, Ibaraki, Japan.
In this work, trivalent rare earth (RE)-rich borate glasses (30 LaO-70 BO, 50 LaO-50 BO, 60 LaO-40 BO, and 50 YO-50 BO) were modeled using ab initio molecular dynamics (AIMD) simulations through the melt-quenching route. It was found that the AIMD-derived structures reproduced the experimental structure factors and B solid-state nuclear magnetic resonance data. Isolated borate units (monomers, dimers, and trimers) terminated with nonbridging oxygen were found in the structures.
View Article and Find Full Text PDFJ Dent
January 2025
Department of Operative Dentistry, Endodontics and Dental Materials, Bauru School of Dentistry, University of São Paulo, Alameda Dr. Otávio Pinheiro Brisolla, 9-75, Bauru, SP 17012-901, Brazil. Electronic address:
Objective: The emergence of new resin composites (RCs) incorporating bioactive ingredients and/or used as bulk-fill materials aims to enhance restorative potential beyond just the mechanical properties. However, this innovation may affect their performance under clinically simulated conditions, such as erosive challenges (EC). This study evaluated the impact of different technologies on the hygroscopic properties of RCs.
View Article and Find Full Text PDFEukaryotic genomes are replete with satellite DNAs (satDNAs), large stretches of tandemly repeated sequences that are mostly underrepresented in genome assemblies. Here we combined nanopore long-read sequencing with a reference-guided assembly approach to generate an improved, high-quality genome assembly, TcasONT, of the model beetle Enriched by 45 Mb in repetitive regions, the new assembly comprises almost the entire genome sequence. We use the enhanced assembly to conduct global and in-depth analyses of abundant euchromatic satDNAs.
View Article and Find Full Text PDFClin Oral Investig
October 2024
Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, 900 Joaquim Sá St, Fortaleza, Ceará,, 60.135-218, Brazil.
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