Purpose: To compare efficacy of aspherical intraocular lenses (IOLs) with spherical IOLs by measuring the ocular and internal higher-order aberrations.

Methods: Two hundred four eyes of 145 patients were evaluated at Kozaki eye clinic after phacoemulsification with implantation of 2 aspherical IOLs (45 eyes with the Hoya FY60AD, and 43 eyes with the Nidek N4-18YG); or 3 spherical IOLs (38 eyes with the Hoya YA60BBR, 32 eyes with the Kowa AU6K and 46 eyes with the Alcon MZ30BD). The 3rd and 4th higher-order aberrations (HOAs) were measured with KR9000PW for a 6-mm-diameter pupil, and then the ocular and internal HOAs were compared between the groups.

Results: The mean internal spherical aberrations at 1 month after surgery were significantly lower in the FY60AD (-0.14 +/- 0.07 microm) and the N4-18YG (-0.23 +/- 0.08 microm) than in the MZ30BD (0.17 +/- 0.10 microm), the YA60BBR (0.16 +/- 0.08 microm) and the AU6K (0.04 +/- 0.06 microm). The mean ocular HOAs were significantly lower in the FY60AD and the N4-18YG than in the other spherical IOLs. The negative correlation between IOL power and spherical aberrations after surgery was significant for both the aspherical IOL groups of FY60AD and N4-18YG.

Conclusions: The correlation between the IOL power and spherical aberrations, and the HOAs after surgery varied depending on the type of IOL.

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