Two cis-acting elements in the p120 gene play important roles in transcription; the region from -537 to -278 is necessary for initiation of transcription, and the region from -1426 to -1223 is necessary for efficient transcription. The distal element(s) which lies upstream of -278 is required for initiation of transcription.
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http://dx.doi.org/10.1128/mcb.10.6.3253-3255.1990 | DOI Listing |
Genes (Basel)
October 2024
Facultad de Medicina, Universidad Nacional Autónoma de Mexico, Mexico City 04360, CP, Mexico.
Background: Dementia causes the loss of functional independence, resulting in a decrease in the quality of life of those who suffer from it.
Aims: This study aimed to investigate the interactions influencing susceptibility to the development of dementia through multifactor dimensionality reduction (MDR).
Methods: the study population was made up of 221 cases and 534 controls.
JAMA Netw Open
September 2024
Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Importance: Extreme heat in the US is increasing due to climate change, while extreme cold is projected to decline. Understanding how extreme temperature along with demographic changes will affect population health is important for devising policies to mitigate the health outcome of climate change.
Objective: To assess the burden of extreme temperature-related deaths in the contiguous US currently (2008-2019) and estimate the burden in the mid-21st century (2036-2065).
JAMA Netw Open
July 2024
Department of Psychology, University of British Columbia, Vancouver, Canada.
Sci Rep
July 2024
Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran, Dr. Hasan Sadikin General Hospital, Prof Eykman Street No 38, Bandung, 40161, Indonesia.
Global challenges in ovarian cancer underscore the need for cost-effective screening. This study aims to assess the role of pretreatment Neutrophil-to-Lymphocyte Ratio (NLR), Lymphocyte-to-Monocyte-Ratio (LMR), Platelet-to-Lymphocyte Ratio (PLR), and CA-125 in distinguishing benign and malignant ovarian tumors, while also constructing nomogram models for distinguish benign and malignant ovarian tumor using inflammatory biomarkers and CA-125. This is a retrospective study of 206 ovarian tumor patients.
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