In the title compound, C(19)H(13)Br(2)NO, the dihedral angle between the rings of the biphenyl group is 53.59 (14)°. The ring of the benzamide group is inclined to the phenyl rings of the biphenyl group by 23.87 (15) and 75.89 (15)°. There are no significant inter-molecular inter-actions in the crystal structure.
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http://dx.doi.org/10.1107/S1600536813000597 | DOI Listing |
J Hazard Mater
November 2024
Energy and Resources Institute, Charles Darwin University, Ellengowan Drive, Purple 12.01.08, Casuarina, NT 0810, Australia. Electronic address:
Contamination of chars with dioxin-like polychlorinated biphenyls (dl-PCB) significantly limits their use and hinders their deployment in the circular bioeconomy, specifically in applications that may lead to dietary exposure. Here, for the first time, we review the levels of contamination of chars produced from pyrolysis and hydrothermal carbonisation (HTC) with dl-PCB congeners. We conduct a detailed and critical examination of the role played by the processing parameters, such as temperature and residence time, and the reaction mechanisms, to detoxify the biomass under an oxygen-free atmosphere during its valorisation.
View Article and Find Full Text PDFJ Mater Chem B
December 2024
Main group Organometallics Optoelectronic Materials and Catalysis lab, Department of Chemistry, National Institute of Technology, Calicut, 673601, India.
Lipid droplets (LDs) are dynamic, multifunctional organelles critical for regulating energy balance, cell signaling, membrane formation, and trafficking. Recent studies have highlighted LDs as emerging cancer biomarkers, with cancer cells typically exhibiting a higher number and viscosity of LDs compared to normal cells. This discovery paves the way for developing molecular probes that can monitor intracellular viscosity changes within LDs, offering a powerful tool for early cancer diagnosis, recurrence monitoring, and therapeutic interventions.
View Article and Find Full Text PDFEur J Med Chem
February 2025
Department of Internal Medicine V, Hematology and Oncology, Tyrolean Cancer Research Institute (TKFI), Comprehensive Cancer Center Innsbruck (CCCI), Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria. Electronic address:
Drug resistance presents a significant challenge in cancer therapy, which has led to intensive research in resistance mechanisms and new therapeutic strategies. In chronic myeloid leukemia (CML), the introduction of Imatinib, the first tyrosine kinase inhibitor (TKI), drastically changed the outcome for patients. However, complete remission still cannot be achieved in a large number of patients in the long term.
View Article and Find Full Text PDFMolecules
September 2024
Leicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.
A focussed library of pyridyl and 2-hydroxyphenyl chalcones were synthesized and tested for growth inhibitory activity against H37Rv, and normal and cancer breast cell lines. Pyridyl chalcones bearing lipophilic A-ring, e.g.
View Article and Find Full Text PDFActa Crystallogr E Crystallogr Commun
September 2024
Department of PG Studies and Research in Physics Albert Einstein Block UCS Tumkur University, Tumkur Karnataka 572103 India.
In the title compound, CHON, the dihedral angle between the aromatic rings of the biphenyl unit is 38.14 (2)° and the C-O-C-C torsion angle in the benz-yloxy benzene fragment is 179.1 (2)°.
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