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Investigating causal relationship among inflammatory cytokines and oropharyngeal cancer: Mendelian randomization.
Discov Oncol
January 2025
Department of Stomatology, Hangzhou Linping District First People's Hospital, Hangzhou, China.
Objectives: This study aims to use Mendelian randomisation to identify the causal relationship between a spectrum of 41 inflammatory cytokines and the development of oropharyngeal cancer.
Methods: This study investigated genetic variants that have been associated with oral and oropharyngeal cancer using data from a large GWAS. Inflammatory cytokine data were obtained from 8293 asymptomatic individuals.
Masquelet's induced membrane technique in the upper limb: a systematic review of the current outcomes.
J Orthop Traumatol
January 2025
Unità Operativa di Ortopedia e Traumatologia, APSS Trento, Largo Medaglie d'oro, 9, 38121, Trento, Italy.
Background: The Masquelet induced membrane technique is a surgical procedure that allows the reconstruction of segmental bone defects using a relatively simple approach that requires minimal resources from both the healthcare facility and the patient. Historically applied to the lower limb, this technique is gaining increasing attention in the literature for its use in the upper limb.
Methods: A systematic review of the literature was conducted using the PubMed and Google Scholar databases to identify all studies reporting the outcomes of the Masquelet induced membrane technique in the long bones of the upper limb (humerus, radius, and ulna) with a sample size of at least 3 patients.
Redox Status-Selective Imaging of Iron in Vegetative and Pathogenic Fungal Cells Using Fluorescent Dyes Synthesized Via Simple Chemical Reactions.
Mol Plant Microbe Interact
January 2025
Phytopathologie und Pflanzenschutz, Institut für Agrar- und Ernährungswissenschaften, Martin-Luther-Universität Halle-Wittenberg, Halle (Saale), Germany.
Iron plays a prominent role in various biological processes and is an essential element in almost all organisms, including plant-pathogenic fungi. As a transition element, iron occurs in two redox states, Fe and Fe, the transition between which generates distinct reactive oxygen species (ROS) such as HO, OH anions, and toxic OH· radicals. Thus, the redox status of Fe determines ROS formation in pathogen attack and plant defense and governs the outcome of pathogenic interactions.
View Article and Find Full Text PDFUnconventional and Powerful Ion Sources for Solid-State Ion Exchange, CuSO and CuPO: Exemplified by the Synthesis of Metastable β-CuGaO from Stable β-LiGaO.
Inorg Chem
January 2025
Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Sendai, Miyagi 980-8577, Japan.
This study introduces a new method for synthesizing Cu-containing metastable phases through ion exchange. Traditionally, CuCl has been used as a Cu ion source for solid-state ion exchanges; however, its thermodynamic driving force is often insufficient for complete ion exchange with Li-containing precursors. First-principles calculations have identified CuSO and CuPO as more powerful alternatives, providing a higher driving force than CuCl.
View Article and Find Full Text PDFA rapid and simple MALDI-TOF MS lipid profiling method for differentiating from .
J Clin Microbiol
January 2025
Department of Mycobacteriology, Leprosy Research Center, National Institute of Infectious Diseases, Higashimurayama, Tokyo, Japan.
, a slow-growing nontuberculous mycobacterium, causes Buruli ulcer, a neglected tropical disease. Distinguishing from related species, including , poses challenges with respect to making accurate identifications. In this study, we developed a rapid and simple identification method based on mycobacterial lipid profiles and used matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) to analyze the lipid profiles of ( = 35) and ( = 19) isolates.
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