Anogenital warts (condyloma acuminatum or venereal warts) are a common sexually transmitted disease in males and females. Common clinical treatment of anogenital warts is conservative, however, in extreme cases conservative therapy is insufficient and surgical excision is required. Giant condyloma acuminata (Buschke-Löwenstein tumour) is an extremely rare clinical type of genital wart, characterised by aggressive down growth into underlying dermal structures. A 55-year-old female presented with cauliflower-like growth over the anogenital and sacral region, earlier diagnosed as condyloma acuminatum which was resistant to conservative therapy. During the period between 2005 and 2008 the patient underwent five surgical procedures. Due to the size and location of the tumour, gynaecological and plastic surgeons were involved in the procedures. In addition, definitive histology examination identified a superficial vulvar carcinoma.
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http://dx.doi.org/10.3892/ol.2012.1027 | DOI Listing |
JAMA Dermatol
January 2025
Department of Medical Oncology, Houston Methodist Hospital, Houston, Texas.
Cureus
November 2024
Emergency Medicine, Public Health Institution Dom Zdravlja Prijedo, Prijedor, BIH.
The giant condyloma acuminatum, known as the Buschke-Löwenstein tumor (BLT), is an uncommon, slow-growing, cauliflower-like tumor located in the anogenital region. It has a high recurrence rate, is sexually transmitted, and is often linked with immunosuppression. This tumor is commonly associated with human papillomavirus (HPV) infection, making HPV one of the most prevalent sexually transmitted infections affecting the perineal and genital regions.
View Article and Find Full Text PDFJ Surg Case Rep
October 2024
Department of General Surgery, Virginia Mason Franciscan Health, 1100 9th Ave, Seattle, WA 98101, United States.
Perineal verrucous carcinoma is a rare variant of squamous cell carcinoma that is mainly treated with surgical excision. In this case report, we present a 58-year-old man with human immunodeficiency virus who presented with an extraordinarily large perineal mass that was ultimately found to be verrucous carcinoma in association with giant condyloma acuminata. He was treated with a wide local excision followed by staged abdominoperineal resection and fasciocutaneous flap reconstruction.
View Article and Find Full Text PDFFront Oncol
August 2024
Department of Thyroid and Breast Surgery, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
GCA, also known as Buschke-Lowenstein tumor, is a rare sexually transmitted disease associated with HPV types 6 and 111. These warts are considered histologically benign, but there is a risk of localized invasion and development of malignancy. This malignant transformation occurs most often in the perianal and vulvar areas, and involvement of other sites is relatively rare2.
View Article and Find Full Text PDFUrology
November 2024
Department of Surgery, Division of Urology, Federal University of São Paulo, São Paulo, São Paulo, Brazil.
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