AI Article Synopsis
- About one third of epilepsy patients do not respond to medications, referred to as pharmacoresistant epilepsy.
- The ketogenic diet can be a highly effective treatment option for some of these patients, and it should be considered early on in their care.
- The review covers various types of ketogenic diets, how they work, their evidence in treating different types of epilepsy, practical guidelines for starting and maintaining the diet, and emerging research on its use in other neurological disorders.
Article Abstract
About one third of patients with epilepsy are pharmacoresistent. For a subgroup of this population, the ketogenic diet can be highly efficacious and should be considered early. This review discusses the different types of ketogenic diet, proposed mechanism of actions and its evidence for use in children and adults with both generalized and focal epilepsies where surgery is not feasible. In addition we discuss a practical approach to diet initiation, maintenance and monitoring for side effects. We also summarize the emerging evidence for the use of ketogenic diet in a broad range of neurological disorders.
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| http://dx.doi.org/10.1017/s0317167100013676 | DOI Listing |
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