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Forsythia viridissima Leaf Extract Inhibits Trabecular Bone Mineral Loss in Rats Induced by a Low-Calcium Diet.
J Nutr Sci Vitaminol (Tokyo)
January 2025
R&D Headquarters, Kracie, Ltd.
The Forsythia has been used in herbal medicine, and the leaf is also expected to contain various putative bioactive substances. In this study, we investigated the effects of Forsythia viridissima leaf extract (FLE) on bone metabolism. The anti-osteoporotic effect of FLE was determined in male rats fed a low-calcium diet.
View Article and Find Full Text PDFPotential impact of obstetric history on postmenopausal fragility fracture risk: A reassessment of the Fracture Risk Assessment Tool.
Jt Dis Relat Surg
January 2025
Gazi Üniversitesi Tıp Fakültesi, Ortopedi ve Travmatoloji Anabilim Dalı, 06560 Yenimahalle, Ankara, Türkiye.
Objectives: This study aimed to evaluate the impact of integrating obstetric parameters into the Fracture Risk Assessment Tool (FRAX) on the precision of risk assessment.
Patients And Methods: In this retrospective study, patients who experienced postmenopausal fragility fractures of the distal radius, proximal femur, or lumbar vertebrae between January 1, 2021, and December 31, 2023, were included. Obstetric histories, along with standard FRAX parameters, were obtained by phone interviews.
Unicortical Versus Bicortical Proximal Locking Screw for Prevention of Peri-Implant Fracture: A Biomechanical Analysis of an Osteoporotic Distal Radius Model.
J Hand Surg Glob Online
November 2024
The Curtis National Hand Center, MedStar Union Memorial Hospital, Baltimore, MD.
Purpose: Osteoporotic patients are at risk of peri-implant fractures after distal radius fixation. A unicortical screw in the proximal hole of the plate can theoretically decrease stress riser formation by eliminating the hole in the far bone cortex. This construct has been proposed in orthopedic literature to prevent peri-implant fractures but has not been tested in an osteoporotic distal radius model.
View Article and Find Full Text PDFModern anatomical locking plates are associated with increased postoperative wound complications and unplanned surgical revisions compared to standard tubular plates in the management of unstable ankle fractures: a comparative cohort study in 595 patients.
Patient Saf Surg
December 2024
Department of Trauma, Hand and Reconstructive Surgery, Rostock University Medical Center, Schillingallee 35, 18057, Rostock, Germany.
Background: The clinical benefit of locking plates in distal fibula fractures has not yet been proven. In addition, the risk of wound complications appears to be higher than with conventional tubular plates. We hypothesize that the benefits of locking plates in terms of biomechanical properties are outweighed by a higher risk of wound complications.
View Article and Find Full Text PDFPercutaneous Kyphoplasty Alleviates Pain Occurring Distal to the Fracture Area Caused by Stage I and II Kümmell Disease.
Pain Physician
November 2024
Department of Orthopedics, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Background: Kümmell disease (KD)-a rare and relatively complex spinal condition-is a type of posttraumatic osteoporotic vertebral compression fracture manifesting as a delayed collapse of a vertebral body. Although most patients with KD present with pain in the fracture area, some present with pain in the rib region or distal lumbosacral region, without pain in the fracture area, which poses challenges for diagnosing and treating KD.
Objective: We aimed to explore whether percutaneous kyphoplasty can alleviate pain distal to the fracture area caused by either Stage I or Stage II KD.
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