Objective: To identify a comprehensive list of features that might discriminate between gout and other rheumatic musculoskeletal conditions, to be used subsequently for a case-control study to develop and test new classification criteria for gout.
Methods: Two Delphi exercises were conducted using Web-based questionnaires: one with physicians from several countries who had an interest in gout and one with patients from New Zealand who had gout. Physicians rated a list of potentially discriminating features that were identified by literature review and expert opinion, and patients rated a list of features that they generated themselves. Agreement was defined by the RAND/UCLA disagreement index.
Results: Forty-four experienced physicians and 9 patients responded to all iterations. For physicians, 71 items were identified by literature review and 15 more were suggested by physicians. The physician survey showed agreement for 26 discriminatory features and 15 as not discriminatory. The patients identified 46 features of gout, for which there was agreement on 25 items as being discriminatory and 7 items as not discriminatory.
Conclusion: Patients and physicians agreed upon several key features of gout. Physicians emphasized objective findings, imaging, and patterns of symptoms, whereas patients emphasized severity, functional results, and idiographic perception of symptoms.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3899/jrheum.121037 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A dataset of annotated free comments on the sensory perception of madeleines for benchmarking text mining techniques.
Data Brief
February 2025
Oniris, INRAE, StatSC, 44300 Nantes, France.
This dataset was created to investigate the impact of data collection modes and pre-processing techniques on the quality of free comment data related to consumers' sensory perceptions. A total of 200 consumers were recruited and divided into two groups of 100. Each group evaluated six madeleine samples (five distinct samples and one replicate) in a sensory analysis laboratory, using different free comment data collection modes.
View Article and Find Full Text PDFRelationship between gout flare states and patient-reported outcomes following allopurinol initiation.
Arthritis Care Res (Hoboken)
January 2025
University of Auckland, Auckland, New Zealand.
Article Synopsis
- Gout flares are crucial indicators of the disease's impact, with specific maximum flare counts linked to acceptable symptom states (PASS) and low disease activity (LDA).
- A study analyzed data from 179 gout patients over 12 months, focusing on flare occurrences and assessing their impact on patient-reported outcomes, including quality of life and illness perception.
- Results showed that while many participants achieved either PASS or LDA, increased flare frequency correlated with higher negative impacts on patients, emphasizing the need for effective flare prevention strategies in gout management.
Sex Differences in Clinical Features in Gout: A Nationwide Retrospective Cohort Study.
J Clin Med
November 2024
Division of Rheumatology, Department of Internal Medicine, Kangwon National University School of Medicine, 156 Baengnyeong-ro, Chuncheon-si 24289, Republic of Korea.
Patients with gout have several coexisting conditions that impact mortality. We analyzed the differences in clinical manifestations among Korean patients with gout and compared the causes of death based on sex using data from the Korean National Health Insurance Service-National Sample Cohort database. We included adults with gout receiving urate-lowering therapy (ULT) from 2002 until 2019.
View Article and Find Full Text PDFTenosynovitis with psammomatous calcifications: Series of 18 cases and review of the literature emphasizing a common source of expert consultation and updated differential diagnosis.
Virchows Arch
December 2024
Department of Pathology, The Johns Hopkins University School of Medicine, 401 N Broadway, Weinberg Building 2245, Baltimore, MD, 21231, USA.
Article Synopsis
- - Tenosynovitis with psammomatous calcifications (TPC) is a rare, non-cancerous condition that often affects women and is thought to result from repetitive use or trauma, commonly appearing at sites like the hands, feet, and wrists.
- - In a study involving 18 new cases, most patients presented with painful masses, and imaging often showed benign characteristics, but many of these cases were misdiagnosed as more serious conditions like gout or tumors.
- - Follow-up on patients (mostly for around 30 months) showed no local recurrences after surgical removal, highlighting the necessity for greater awareness among medical professionals regarding TPC.
Imaging comparative analysis of familial and sporadic gout in Chinese men by multijoint ultrasonography.
Front Med (Lausanne)
November 2024
Department of Ultrasound, First Affiliated Hospital, Clinical Medical College of Chengdu Medical College, Chengdu, China.
Objective: This study aimed to compare the imaging features of bilateral knees, ankles, and the first metatarsophalangeal joint using high-frequency ultrasonography in male patients with familial and sporadic primary gout and sought to elucidate the relationship between the presence of tophi and various clinical indicators.
Method: Male patients with primary gouty arthritis (GA) in the acute phase presenting to the Department of Rheumatology and Immunology at the First Affiliated Hospital of Chengdu Medical College from November 2020 to June 2022 were enrolled and classified into familial and sporadic gout groups. Comparative analyses of their clinical data and ultrasonographic imaging findings of the knees, ankles, and first metatarsophalangeal joints were performed between the groups.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!