AI Article Synopsis
- The study investigates the likelihood and identifying factors related to relapse in individuals who have recovered from Cannabis Use Disorders (CUD).
- The research analyzed data from 2,350 individuals who were in full remission and found a 6.63% relapse rate over an average follow-up period of 3.6 years.
- Key findings highlighted that longer time in remission reduced relapse risk, while having a history of conduct disorder or major depressive disorder increased it, suggesting targeted treatment could enhance sustained remission.
Article Abstract
Background: This study aims to estimate the odds and predictors of Cannabis Use Disorders (CUD) relapse among individuals in remission.
Methods: Analyses were done on the subsample of individuals with lifetime history of a CUD (abuse or dependence) who were in full remission at baseline (Wave 1) of the National Epidemiological Survey of Alcohol and Related Conditions (NESARC) (n=2350). Univariate logistic regression models and hierarchical logistic regression model were implemented to estimate odds of relapse and identify predictors of relapse at 3 years follow up (Wave 2).
Results: The relapse rate of CUD was 6.63% over an average of 3.6 year follow-up period. In the multivariable model, the odds of relapse were inversely related to time in remission, whereas having a history of conduct disorder or a major depressive disorder after Wave 1 increased the risk of relapse.
Conclusions: Our findings suggest that maintenance of remission is the most common outcome for individuals in remission from a CUD. Treatment approaches may improve rates of sustained remission of individuals with CUD and conduct disorder or major depressive disorder.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338368 | PMC |
| http://dx.doi.org/10.1016/j.drugalcdep.2013.01.013 | DOI Listing |
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