Ester hydrolysis by a histidine-containing cavitein.

Bioorg Med Chem Lett

Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC, Canada V6T 1Z1.

Published: March 2013

We have used a template-assembled synthetic protein (TASP) to investigate catalytic function in ester hydrolysis. A histidine-containing cavitein has been found to catalyze ester hydrolysis with a rate increase of 18 times that of background.

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Source
http://dx.doi.org/10.1016/j.bmcl.2013.01.063DOI Listing

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