Background And Objective: Ultra wide field technology was originally designed for use in children. The purpose of this study was to evaluate ultra wide field fluorescein angiography (UWFFA) in children.
Patients And Methods: Retrospective case series of patients younger than 13 years who underwent UWFFA. Angiographic findings and their impact on diagnosis and management were assessed. UWFFA quality was evaluated, including phases of the angiogram available in each study, field of view, and artifacts.
Results: Forty images of 16 patients with a mean age of 9.3 years were included. Peripheral angiographic findings such as vasculitis, telangiectasia, and neovascularization were present in 12 of 16 patients (75%). Seven of 16 patients (43.8%) had images during the arterial phase, and 16 of 16 patients (100%) had venous and recirculation phases captured.
Conclusion: UWFFA was successfully performed in this group of children. The macula and periphery were adequately imaged, obtaining important information for documentation, diagnosis, and management.
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http://dx.doi.org/10.3928/23258160-20121221-14 | DOI Listing |
Angew Chem Int Ed Engl
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Beijing University of Chemical Technology, State Key Laboratory of Organic-Inorganic Composites, 15 North Third Ring Road East, 37830, Beijing, CHINA.
Polymers with strong electron-withdrawing groups (e.g., cyano-containing polymers) are attractive for a wide range of applications due to their high dielectric constant and outstanding electrochemical stability.
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RIKEN Center for Biosystems Dynamics Research, Suita‐shi, Osaka, Japan
Background: In aging societies, neurodegenerative diseases, such as Alzheimer's disease, are receiving attention. These diseases are primary targets for preemptive medicine, emphasizing the importance of early detection and preventive treatment before the onset of severe, treatment‐resistant damages. However, there is a lack of comprehensive investigation of lesions and molecular targets in the entire organ, whereas spatial identification of early‐stage lesions is potentially overlooked at the single‐cell level.
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Department of Pharmacy, The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital of Wannan Medical College Wuhu China
Ultra-high dose-rate (FLASH) radiotherapy serves as an ideal procedure to treat tumors efficiently without harming normal tissues and has demonstrated satisfactory antitumor effects in multiple animal tumor models. However, the biological mechanisms of FLASH radiotherapy have not yet been fully elucidated, and the small number of devices delivering FLASH dose rate has limited its wide application. This review summarizes the possible biological mechanisms and antitumor effects of FLASH radiotherapy, its application in nanotherapeutic strategy, as well as its challenges and future development.
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January 2025
Division of Computer, Electrical and Mathematical Sciences and Engineering, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Saudi Arabia.
We propose and demonstrate a data-driven plasmonic metascreen that efficiently absorbs incident light over a wide spectral range in an ultra-thin silicon film. By embedding a double-nanoring silver array within a 20 nm ultrathin amorphous silicon (a-Si) layer, we achieve a significant enhancement of light absorption. This enhancement arises from the interaction between the resonant cavity modes and localized plasmonic modes, requiring precise tuning of plasmon resonances to match the absorption region of the silicon active layer.
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Shuwen Biotech Co., Ltd., Moganshan National High tech Zone, Building 3, No. 333, Changhong Middle Street, Deqing, China.
Over the past five years, circulating tumor DNA (ctDNA) testing has emerged as a game-changer in cancer research, serving as a less invasive and highly sensitive method to monitor tumor dynamics. CtDNA testing has a wide range of potential applications in breast cancer (BC) management, including diagnosis, monitoring treatment responses, identifying resistance mutations, predicting prognosis, and detecting future relapses. In this review, we focus on the prognostic and predictive value of ctDNA testing for BC in both neoadjuvant and adjuvant settings.
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