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Bridging the gap in early diagnosis of hidradenitis suppurativa.
Arch Dermatol Res
January 2025
Center for Dermatology Research, Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Causal association between body fat percentage and hidradenitis suppurativa: A two-sample Mendelian randomization study.
J Eur Acad Dermatol Venereol
January 2025
Centre for Molecular Medicine and Biobanking, University of Malta, Msida, Malta.
A Patient With Concurrent Hidradenitis Suppurativa and Porokeratosis Palmaris et Plantaris Disseminata: Case Report and Review of Autoinflammatory Keratinization Diseases.
J Cutan Pathol
January 2025
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
The term autoinflammatory keratinization diseases (AIKDs) was recently proposed as a unifying concept for diseases characterized by inflammation in the epidermis and upper dermis which leads to hyperkeratosis, caused by genetic perturbations of the innate immune system. We present a case of a patient with hidradenitis suppurativa and porokeratosis, two AIKDs, followed by a review of these conditions as well as other AIKDs. This case was distinguished by hypertrophic porokeratoses involving cystic hair follicles, showing histopathologic features of both conditions within single biopsy specimens.
View Article and Find Full Text PDFRF - Metformin as part of the therapeutic armamentarium of hidradenitis suppurativa.
Actas Dermosifiliogr
December 2024
Servicio de Dermatología. Hospital Universitario de Guadalajara, Guadalajara, España.
Janus-kinase inhibitor use in immune-mediated inflammatory diseases beyond licensed indications: A scoping review.
Autoimmun Rev
December 2024
Rheumatology Department, Guy's and St Thomas' NHS Trust, London, United Kingdom.
Introduction: The use of Janus kinase inhibitors (JAKis) in immune-mediated inflammatory diseases (IMIDs) beyond licence is expanding rapidly. The aim of this scoping review was to identify and present the available evidence on the efficacy of JAKis in all conditions without marketing authorisation.
Methods: Through a systematic literature search we identified studies including 5 or more patients that assessed the use of any JAKi for any efficacy outcome.
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