The Chinese human adenovirus 7 (HAdV7) 0901HZ/ShX/CHN/2009 was isolated from the hydrothorax fluid of an infant with fatal pneumonia in Shaanxi, China, in 2009. Comparison of the entire genome with the genomes of the other 10 strains of HAdV7 from GenBank revealed homologies of 89.9 to 99.9%, with geographic polymorphism among HAdV-7 field strains circulating in mainland China.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569294 | PMC |
| http://dx.doi.org/10.1128/genomeA.00182-12 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A highly contagious infection caused by human adenovirus species D (HAdV-D), epidemic keratoconjunctivitis (EKC) results in corneal subepithelial infiltration (SEI) by leukocytes, the hallmark of the infection. To date, the pathogenesis of corneal SEI formation in EKC is unresolved. HMGB1 (high-mobility group box 1 protein) is an alarmin expressed in response to infection and a marker of sepsis.
View Article and Find Full Text PDFHypoxia-Inducible Factor-1α Regulates BNIP3-Dependent Mitophagy and Mediates Metabolic Reprogramming Through Histone Lysine Lactylation Modification to Affect Glioma Proliferation and Invasion.
J Biochem Mol Toxicol
February 2025
Department of Neurosurgery, the First Affiliated Hospital of Harbin Medical University, Harbin, China.
Objective: Gliomas are the predominant form of malignant brain tumors. We investigated the mechanism of hypoxia-inducible factor-1α (HIF-1α) affecting glioma metabolic reprogramming, proliferation and invasion.
Methods: Human glioma cell U87 was cultured under hypoxia and treated with small interfering (si)HIF-1α, si-B cell lymphoma-2/adenovirus E1B 19-kDa interacting protein 3 (siBNIP3), si-YT521-B homology domain 2 (siYTHDF2), 3-methyladenine and 2-deoxyglucose, with exogenous sodium lactate-treated normally-cultured cells as a lactate-positive control.
Betagenin ameliorates diabetes by inducing insulin secretion and β-cell proliferation.
J Biol Chem
January 2025
Division of Experimental Animal, Hidaka Branch, Biomedical Research Center, Saitama Medical University, Saitama, Japan; Research Center for Genomic Medicine, Saitama Medical University, Saitama, Japan. Electronic address:
Recent success with the use of glucagon-like peptide-1 (GLP-1) receptor analogs and dipeptidyl peptidase-4 (DPP-4) inhibitors for the treatment of patients with diabetes has highlighted the role of the intestine as an endocrine organ. Gut-derived hormones, including GLP-1, glucose-dependent insulinotropic polypeptide (GIP), and ghrelin, have important roles in the control of energy metabolism and food intake, and are associated with the metabolic syndrome. In this study, we isolated and identified a new intestine-derived hormone, betagenin, and showed that it stimulates insulin secretion and β-cell proliferation and suppresses β-cell apoptosis.
View Article and Find Full Text PDFAbundance and possibilities of crAssphage and PMMoV as a viral indicator in raw sewage in wastewater treatment plants.
Sci Total Environ
January 2025
Department of Environmental Health Sciences, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, United States of America; Organization for Public Health and Environment Management, Lalitpur, Nepal; Water & Energy Sustainable Technology (WEST) Center, University of Arizona, Tucson, AZ, United States of America; Center of Research Excellence in Wastewater based Epidemiology, Morgan State, Baltimore, MD, United States of America. Electronic address:
Given their abundance in human fecal samples, crAssphage and Pepper Mild Mottle Virus (PMMoV) are proposed as indicators for human enteric viruses. This study measured crAssphage and PMMoV in raw sewage samples (n = 24) between June 2014 and May 2015 from two wastewater treatment facilities in southern Arizona, USA. Both crAssphage and PMMoV were detected in nearly 100% of samples.
View Article and Find Full Text PDFDogs are a susceptible species to human adenovirus 36 infection: New insights into the host range of the virus causing infectious obesity.
Vet Microbiol
January 2025
Division of Microbiology, Department of Pathology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, C.K. Norwida 31 Street, Wrocław 50-375, Poland. Electronic address:
The prevalence of obesity within the human population is escalating globally yearly. Obesity constitutes a complex ailment with diverse etiological factors. Recently, the infectious side of obesity aetiology, implicating pathogens such as human adenovirus 36 (HAdV-D36), has gained attention.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!