AI Article Synopsis
- Transcranial magnetic stimulation (TMS) is a non-invasive method used to assess the functionality of motor corticospinal tracts and measure cortical excitability.
- Over the past 30 years, various TMS protocols have been developed, including single-pulse and repetitive TMS, which enhance our ability to detect changes in the brain's excitability related to neurological disorders.
- This review summarizes existing research on TMS's role in understanding cortical excitability and its implications for brain disorders.
Article Abstract
Transcranial magnetic stimulation (TMS) is a technique developed to non-invasively investigate the integrity of human motor corticospinal tracts. Over the last three decades, the use of stimulation paradigms including single-pulse TMS, paired-pulse TMS, repetitive TMS, and integration with EEG and functional imaging have been developed to facilitate measurement of cortical excitability.Through the use of these protocols, TMS has evolved in-to an excellent tool for measuring cortical excitability.TMS has high sensitivity in detecting subtle changes in cortical excitability, and therefore it is also a good measure of disturbances associated with brain disorders. In this review, we appraise the current literature on cortical excitability studies using TMS in neurological disorders.We begin with a brief overview of current TMS measures and then show how these have added to our understand-ing of the underlying mechanisms of brain disorders.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812767 | PMC |
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