AI Article Synopsis
- Heart failure often shows symptoms like shortness of breath, swelling, and fatigue, particularly during physical activity or when lying down.
- The left ventricular ejection fraction (LVEF) is crucial for identifying patients who might benefit from specific medical treatments or devices.
- Certain medications and devices, such as ACE inhibitors, beta blockers, and cardiac defibrillators, can significantly improve health outcomes, especially for patients with a low LVEF of less than 35%.
Article Abstract
Heart failure (HF) often presents as dyspnea either with exertion and/or recumbency. Patients also experience dependent swelling and fatigue. Measurement of the left ventricular ejection fraction (LVEF) identifies HF patients who may respond to pharmacologic therapy and/or electrophysiologic device implantation. Angiotension converting enzyme inhibitors, beta blockers, and aldosterone inhibitors can significantly lower the mortality and morbidity of HF in patients with an LVEF less than 35%. Cardiac defibrillators and biventricular pacemakers can also improve outcomes in selected patients with a decreased LVEF. The authors provide a guide for therapeutic decisions based on the inclusion criteria of the major clinical trials.
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| http://dx.doi.org/10.1016/j.pop.2012.11.010 | DOI Listing |
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