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| http://dx.doi.org/10.1503/cmaj.120592 | DOI Listing |
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Deep learning based decision-making and outcome prediction for adolescent idiopathic scoliosis patients with posterior surgery.
Sci Rep
January 2025
Department of Orthopedics, Shanghai Changhai Hospital, Shanghai, 200433, China.
With the emergence of numerous classifications, surgical treatment for adolescent idiopathic scoliosis (AIS) can be guided more effectively. However, surgical decision-making and optimal strategies still lack standardization and personalized customization. Our study aims to devise proper deep learning (DL) models that incorporate key factors influencing surgical outcomes on the coronal plane in AIS patients to facilitate surgical decision-making and predict surgical results for AIS patients.
View Article and Find Full Text PDFData-driven exploration of weak coordination microenvironment in solid-state electrolyte for safe and energy-dense batteries.
Nat Commun
January 2025
Shenzhen Geim Graphene Center, Tsinghua-Berkeley Shenzhen Institute & Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, P. R. China.
The unsatisfactory ionic conductivity of solid polymer electrolytes hinders their practical use as substitutes for liquid electrolytes to address safety concerns. Although various plasticizers have been introduced to improve lithium-ion conduction kinetics, the lack of microenvironment understanding impedes the rational design of high-performance polymer electrolytes. Here, we design a class of Hofmann complexes that offer continuous two-dimensional lithium-ion conduction channels with functional ligands, creating highly conductive electrolytes.
View Article and Find Full Text PDFImpact of Financial Incentives and Department Size on Scholarly Activity Output.
Ann Fam Med
January 2025
Department of Family and Preventive Medicine, Emory University, Atlanta, Georgia.
Purpose: Family medicine research is essential to improving population health. It has the unique ability to answer questions about health care outcomes and use those insights to impact communities. Increasing research capacity continues to be a challenge; however, recent literature has touted the success of incentivization in several academic medicine specialties.
View Article and Find Full Text PDFContinuity and locum use for acute consultations: observational study of subsequent workload.
Br J Gen Pract
January 2025
University of Exeter Medical School, University of Exeter, Exeter; consultant, St Leonard's Research Practice, Exeter, UK.
Background: Workload is probably the biggest challenge facing general practice and little is known about any modifiable factors. For GPs, both continuity and locum status are associated with differences in outcomes.
Aim: To determine whether practice and hospital workload after an index acute consultation depend on the type of GP consulted (locums and practice GPs with [regular] and without [non-regular] continuity, and locums).
Impact of Race/Ethnicity on Clinical and Genomic Characteristics, Trial Participation, and Genotype-Matched Therapy among Patients with Metastatic Breast Cancer.
Clin Cancer Res
January 2025
Massachusetts General Hospital Cancer Center, Boston, MA, United States.
Background: Race/ethnicity may affect outcomes in metastatic breast cancer (MBC) due to biological and social determinants. We evaluated the impact of race/ethnicity on clinical, socioeconomic, and genomic characteristics, clinical trial participation, and receipt of genotype-matched therapy among patients with MBC.
Methods: A retrospective study of patients with MBC who underwent cell-free DNA testing (cfDNA, Guardant360â, 74 gene panel) between 11/2016 and 11/2020 was conducted.
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