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Quantifying and characterizing proanthocyanidins in cranberries in relation to urinary tract health. | LitMetric

Quantifying and characterizing proanthocyanidins in cranberries in relation to urinary tract health.

Anal Bioanal Chem

Complete Phytochemical Solutions, LLC, Cambridge, WI 52523, USA.

Published: May 2013

AI Article Synopsis

  • The "A-type" proanthocyanidins found in cranberries are beneficial compounds that help prevent urinary tract infections (UTIs) and promote urinary tract health.
  • Popular cranberry products, including juice, fresh and dried fruit, and dietary supplements, are consumed for their high levels of these proanthocyanidins.
  • Recent advancements in analytical techniques, such as mass spectrometry and liquid chromatography, allow for better measurement and assessment of the quality and efficacy of cranberry products.

Article Abstract

The "A-type" proanthocyanidins in cranberry fruit (Vaccinium macrocarpon Ait.) are bioactive components associated with prevention of urinary tract infections (UTI). Cranberry juice, fruit (fresh and dried), functional foods, and cranberry dietary supplements are promoted for prevention of UTI and for maintenance of urinary tract health (UTH), on the basis of their content of cranberry proanthocyanidins (c-PAC) with "A-type" interflavan bonds. With increasing consumer use of cranberries for maintenance of UTH and an expanding number of commercial cranberry products of different types, the availability of unified methods for measuring levels of c-PAC is important. This review discusses quantitative and qualitative analysis of c-PAC with "A-type" interflavan bonds in relation to their biological activity for UTI prevention. The integrity (including authenticity, standardization, efficacy, and safety) of cranberry fruit, juices, and dietary supplements may now be measured by using recent advances in mass spectrometry, liquid chromatography, production of c-PAC standards, and improved simple quantitative techniques.

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Source
http://dx.doi.org/10.1007/s00216-013-6750-3DOI Listing

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