Chromatin regulatory complexes are well known regulators of stem cell fate; however, the mechanisms regulating their activity are not well understood. In this issue of Cell Stem Cell, Bao et al. (2013) show that ACTL6a inhibits targeting of the SWI/SNF complex to differentiation genes, thereby preserving the epidermal progenitor state.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454396 | PMC |
http://dx.doi.org/10.1016/j.stem.2013.01.011 | DOI Listing |
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!