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Cochlear Mechanics Are Preserved After Inner Ear Delivery of Gold Nanoparticles.
Int J Mol Sci
December 2024
Caruso Department of Otolaryngology-Head and Neck Surgery, University of Southern California, Los Angeles, CA 90033, USA.
Novel therapeutic delivery systems and delivery methods to the inner ear are necessary to treat hearing loss and inner ear disorders. However, numerous barriers exist to therapeutic delivery into the bone-encased and immune-privileged environment of the inner ear and cochlea, which makes treating inner ear disorders challenging. Nanoparticles (NPs) are a type of therapeutic delivery system that can be engineered for multiple purposes, and posterior semicircular canal (PSCC) infusion is a method to directly deposit them into the cochlea.
View Article and Find Full Text PDFTigers in their new territory: intraspecific interactions among the reintroduced tiger population in Panna Tiger Reserve, Central India.
Sci Rep
January 2025
Wildlife Institute of India, Dehradun, 248001, Uttarakhand, India.
Intra-specific interactions among top carnivores are among the most intriguing behavioural aspects and essential components of population dynamics. Static interactions pertain to space use, while dynamic interactions involve spatio-temporal patterns influenced by social structure, distribution, mate selection, and density. Previous studies have focused on static interactions, successfully estimating spatial overlap but leading to a knowledge gap of dynamic interaction to be able to compute attraction and avoidance on similar spatio-temporal scales.
View Article and Find Full Text PDFFerumoxytol-enhanced MRI of retroplacental clear space disruption in placenta accreta spectrum.
Placenta
January 2025
Department of Radiology, Baylor College of Medicine, Houston, TX, 77030, USA; The Singleton Department of Radiology, Texas Children's Hospital, Houston, TX, 77030, USA. Electronic address:
Introduction: Placenta accreta spectrum (PAS) occurs when the placenta is pathologically adherent to the myometrium. An intact retroplacental clear space (RPCS) is a marker of normal placentation. In this study, we investigate use of the FDA-approved iron supplement ferumoxytol for contrast-enhanced MRI of the RPCS in mouse models of normal pregnancy and PAS.
View Article and Find Full Text PDFMicroaggressions and Cultural Ruptures in Psychiatry: Extending Multicultural Counseling Orientation to Psychiatric Services.
Focus (Am Psychiatr Publ)
January 2025
Department of Educational Psychology (Rudecindo, Tao, Imel) and Huntsman Mental Health Institute, Department of Education, Culture, & Society, and Ethnic Studies Program (Smith), University of Utah, Salt Lake City; Perelman School of Medicine, University of Pennsylvania, Philadelphia (Kuo).
Racial microaggressions and cultural ruptures have a significant impact on mental health care for Black, Indigenous, and people of color (BIPOC) communities. This article reviews the application of the multicultural counseling orientation framework in psychiatry to address these challenges and improve therapeutic outcomes. The authors outline strategies to integrate cultural humility into psychiatric practice, with an emphasis on self-reflection, feedback, and the recognition of microaggressions.
View Article and Find Full Text PDFSeeking and encountering online information for menstrual health: a qualitative study among adolescent schoolgirls in Gianyar Regency and Denpasar City, Bali, Indonesia.
Sex Reprod Health Matters
January 2025
Senior Research Fellow, Maternal, Child and Adolescent Health Program, Burnet Institute, Melbourne, VIC, Australia; Honorary Research Fellow, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia.
Sufficient and accurate information is a requirement for menstrual health and supports adolescents in realising their human rights. As mobile connectivity increases globally, many young people may seek or encounter menstrual health information online through web-based platforms, social media, or health apps. Despite the relevance of online information, menstrual health research and programming have focused on formal and school-based learning.
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