Background: A thrombus straddling a patent foramen ovale (i.e., impending paradoxical embolism) is a very rare event. Most cases have been reported at autopsy only after finding a patent foramen ovale and arterial emboli. Patent foramen ovale in the population is common.
Objectives: The objective of this case report is to remind physicians that common presentations can have uncommon causes. Some of these uncommon causes are easy to find and may significantly change outcomes if treated early.
Case Report: We present the case of a dyspneic patient with concomitant pulmonary embolism, deep vein thrombosis, and impending paradoxical embolism. Emergency Physicians should be aware that dyspnea may be the only initial symptom. Although dyspnea may be linked to a pulmonary embolus, it may not represent the entire clinical picture. A thrombus formed within a patent foramen ovale portends the possibility of a larger pulmonary embolus and an arterial embolus.
Conclusion: Early detection of an impending paradoxical embolism may result in an improved outcome. Treatment choices consist of anticoagulation, thrombectomy, or thrombolysis. Choice of treatment is difficult but should be made quickly to reduce the possibility of adverse patient outcomes.
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http://dx.doi.org/10.1016/j.jemermed.2012.11.046 | DOI Listing |
Int J Equity Health
October 2024
Medical Oncology Department, VI University Hospital, Marrakech, Mohammed, 40000, Morocco.
Background: The cost of cancer drugs presents a significant challenge to accessibility of treatment worldwide. Projections indicate that by 2040, two-thirds of cancer cases will occur in low- and middle- income countries. Paradoxically, despite this impending burden, LMICs command less than 5% share of global resources for treating cancer.
View Article and Find Full Text PDFOxf Med Case Reports
August 2024
Yale University School of Medicine Department of Cardiology, New Haven, CT 06510, United States.
Mayo Clin Proc
September 2024
Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
J Cardiothorac Surg
March 2024
Department of Cardiovascular Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.
Background: Paradoxical embolism is a rare cause of acute arterial occlusion. This phenomenon arises when embolic material travels from the venous system crosses an abnormal shunt such as patent foramen ovale, atrial septal defects, ventricular septal defects, or pulmonary arteriovenous malformations, into the arterial system. Impending paradoxical embolism refers to the presence of an entrapped thrombus in the patent foramen ovale.
View Article and Find Full Text PDFJACC Case Rep
March 2024
HonorHealth/Thompson Peak Medical Center, Scottsdale, Arizona, USA.
Thrombus-in-transit through patent foramen ovale (PFO) is an extremely rare diagnosis that can often be associated with pulmonary embolism. Currently, data exists to guide management options; however, there is no medical consensus with regard to the optimal treatment strategy for thrombus-in-transit through PFO.
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