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Background: Meconium is thick black-green fetal intestinal content starting from the early first trimester of gestation. Unfortunately, if it is released into the amniotic cavity due to any cause, it can be associated with neonatal mortality and morbidity.

Objective: To identify the factors associated with meconium-stained amniotic fluid among mothers undergoing emergency cesarean section in specialized hospitals cross-sectional study in south central Ethiopia from August 1, 2022, to 30, October 2022.

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Article Synopsis
  • Amniotic fluid embolism (AFE) is a rare but severe complication during childbirth that can lead to rapid failure of multiple organ systems and significant maternal mortality.
  • A case study involving a 31-year-old woman induced for labor revealed AFE's unpredictability, as she developed sudden fetal distress and hypoxia, leading to an emergency cesarean delivery.
  • Despite the high mortality associated with AFE, both the mother and the infant survived and were doing well six months later, highlighting the importance of prompt diagnosis and treatment options like the "A-OK" protocol.
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Amniotic Fluid as a Potential Treatment for Vocal Fold Scar in a Rabbit Model.

J Voice

January 2025

Department of Otolaryngology - Head and Neck Surgery, University of Utah, Salt Lake City, UT; Department of Surgery, University Utah, Salt Lake City, UT.

Objectives/hypothesis: Vocal fold (VF) injury and chronic inflammation can progress to scarring, which is notoriously difficult to treat. Human amniotic fluid (AF) has potential for VF wound healing in a rabbit model, and we hypothesized that AF would demonstrate wound healing properties superior to hyaluronic acid (HA) over time.

Study Design: Randomized, controlled trial.

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Purpose: The aim of the present study was to establish a SYBR Green-based real-time PCR assay for detection of the Nc5 segment from the Neospora caninum genome.

Methods: The oligonucleotides sequences targeting the Nc5 gene previously reported and designed in-house were validated. Two Primer sets were evaluated and tested in four different combinations.

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Amniotic fluid (AF)-derived exosomal miRNA have been explored as potential contributors to the pathogenesis of Tetralogy of Fallot (TOF). This study aimed to investigate the expression profiles of AF-derived exosomal miRNAs and their potential contribution to TOF development. Exosomes were isolated from AF samples obtained from pregnant women carrying fetuses diagnosed with TOF.

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