Synthesis of 6'-deoxy-6'-fluorosucrose.

Carbohydr Res

Department of Chemistry, University of Missouri-Columbia, Columbia, MO 65211, United States.

Published: March 2013

A facile synthesis of 6'-deoxy-6'-fluorosucrose has been developed. The title compound is available in six linear steps in 44% overall yield from commercially available sucrose. The synthesis involves rapid and convenient fluorination and deprotection conditions. This procedure would be very useful for the incorporation of radioactive [(18)F].

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http://dx.doi.org/10.1016/j.carres.2012.12.001DOI Listing

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