Objective: To investigate the clinical characteristics of pulmonary hilum Castleman's disease.
Methods: The clinical characteristics of 4 patients diagnosed with pulmonary hilum Castleman's disease in our department were analysed and compared with findings in relevant literature.
Results: Gender and age were not associated with Castleman's disease. The disease was often identified in physical examinations with atypical clinical symptoms. Chest CT was the most common and valuable diagnostic method revealing soft tissue mass near the pulmonary hilum. Gross-total resection of the tumor and (or) lobectomy through a combined posterior trans-thoracic approach were commonly performed, with good prognosis.
Conclusion: Hilum Castleman's disease can be effectively diagnosed and treated.
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Radiol Case Rep
August 2024
Addis Ababa University, College of Health Sciences, Department of Urology, Addis Ababa, Ethiopia.
Castleman's disease is a rare benign lymphangioproliferative disorder. The hyaline vascular subtype has a better outcome and is curable after surgical resection. Typically, Castleman disease manifests in the thorax, with rare reports of a renal hilum location.
View Article and Find Full Text PDFFront Surg
August 2023
Division of Nephrology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
Castleman disease is a rare heterogeneous lymphoproliferative disorder of unknown etiology. Unicentric Castleman disease (UCD) is more common. UCD can occur at any site where lymphatic tissue exists, most commonly in the mediastinum, neck, and abdominal cavity, etc.
View Article and Find Full Text PDFBMJ Case Rep
August 2023
Urology, All India Institute of Medical Sciences, New Delhi, Delhi, India.
A man in his 50s presented with shortness of breath and was found to have a large paracaval mass, which on further evaluation with CT, showed a large heterogeneously enhancing mass lesion adjacent to right renal hilum. His 24-hour urinary metanephrines and nor-metanephrines were normal. In view of location and features on CT, paraganglioma was considered as a possibility.
View Article and Find Full Text PDFThorac Cancer
June 2022
Department of Thoracic Surgery, Clinical Research Institute, National Hospital Organization Kyushu Medical Center, Fukuoka, Japan.
Castleman disease is a rare disease borne of a B cell lymphoproliferative disorder of uncertain cause. Standard therapy for the unicentric type of Castleman disease localized as a single mass or single lymph-node station is surgical extirpation. Nevertheless, in the thoracic cavity, unresectable cases or cases of incomplete extirpation of the tumor without lung scarring owing to tumor size/location have been noted.
View Article and Find Full Text PDFAnn Med Surg (Lond)
July 2021
Universidad San Francisco de Quito (USFQ), Quito, Ecuador.
Introduction And Importance: Castleman's disease was first reported by Benjamin Castleman et al., in 1954 and described it as a sporadic lymphoproliferative disorder. The pathophysiology to this day is still unknown, although IL-6 is suspected to play an important role.
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