The lifetime of Er3+ and 4I13/2 energy level is of very significance for evaluating the application potential of Er(3+)-doped materials in optical communication. In the present article, based on the Er3+ excited state absorption upconversion (UC) luminescence under 980 nm double-pulse injection LD excitation, the authors detected the red UC luminescence intensity under different time gap between double pulses, then according to the dependence between UC red luminescence intensity and time gap between double pulses, deduced the fitting formula for obtained medial energy level lifetime of Er3+, and actualized the measurement of infrared level lifetime in visible region. So, combining photomultiplier tube (R2658) with double-pulse injection LD module with controllable time gap and synchronous pulse sample, we can obtain all the infrared level lifetime of Er3+, and this is a cost saving lifetime measurement system with micros resolution.
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Background: Loss of recognition memory has been hypothesized to be a potential behavioral marker of neurodegenerative disease given decreases in both recollection and familiarity reported in both MCI (Mild Cognitive Impairment) and AD (Alzheimer's Disease). Stage III CTE (Chronic Traumatic Encephalopathy) involves p-tau deposition in the medial temporal lobe, impacting memory. Decreases of both familiarity and recollection are promising potential markers of CTE related neurodegeneration following TBI (Traumatic Brain Injury).
View Article and Find Full Text PDFCancer Res Commun
January 2025
University of British Columbia, Vancouver, BC, Canada.
With evidence that salpingectomy is effective in preventing high grade serous carcinoma, it is time to consider offering this procedure to people at higher-than-average lifetime risk for ovarian cancer, despite not having a pathogenic genetic variant that increases risk for ovarian cancer. This targeted approach has potential to be effective at reducing ovarian cancer incidence, and unlike opportunistic salpingectomy is focused on people with an increased lifetime risk of ovarian cancer. However, the acceptability of this approach within the population of potential patients remains unknown.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Department of Neurology, and Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Background: Over 30 million Americans have diabetes, with 9 million likely undiagnosed. Diabetes is associated with cognitive decline and risk for Alzheimer's disease and related dementia (ADRD). The lifetime impact of diabetes and prediabetes on cognition may be cumulative.
View Article and Find Full Text PDFBackground: Some individual-level interventions for dementia risk factors could be cost saving. We aimed to estimate the cost effectiveness of population-level interventions for tackling dementia risk factors. We found such interventions for tobacco smoking, excess alcohol use, diet modification to decrease hypertension and obesity, air pollution, and head injury.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Seoul National University College of Medicine, Seoul, Korea, Republic of (South).
Background: The global increase in the aging population has led to a corresponding rise in dementia cases. This study explores the potential link between occupational toxin exposure and the incidence of dementia, aiming to identify high-risk populations.
Method: We analyzed data from 2,485 male participants aged 60 and over in the Korean Longitudinal Study on Cognitive Ageing and Dementia (KLOSCAD).
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