This study reports reliability and validity of the Dutch Reactive-Proactive Aggression Questionnaire (RPQ). In total, 845 participants completed the RPQ along with other measures of aggression. Groups consisted of non-offender participants, criminal offenders, youngsters (age 6-18), and adults (age above 18). Test-retest stability in a subsample of 324 childhood arrestees was good (all ICC's > 0.41). A confirmatory factor analysis supported the same two-factor structure as in the original RPQ. Convergent validity was adequate (all r's > 0.16). Moreover, results demonstrated that the proactive and reactive subscales were differentially related to measurements of callousness and impulsiveness, respectively. Criterion validity was shown in that non-offender subjects demonstrated significantly lower RPQ scores than offender samples. Finally, construct validity was demonstrated in that violent offenders showed higher aggression scores than non-violent offenders. Proactive aggression showed different developmental trajectories within non-offender versus criminal samples, indicating that this form of aggression may be more pathological.
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RSC Chem Biol
January 2025
Bioorganic Chemistry Laboratory, New Chemistry Unit, Jawaharlal Nehru Centre for Advanced Scientific Research Jakkur P.O. Bengaluru Karnataka 560064 India
Reactive oxygen, nitrogen and sulfur species (RONSS) collectively encompasses a variety of energetically dynamic entities that emerge as inherent characteristics of aerobic life. This broad category includes reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS). A conundrum arises from the indispensable role of RONSS in redox signalling, while its overproduction in the mitochondria poses deleterious effects.
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Department of Dermatology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.
Background: The effectiveness of crisaborole for proactive treatment of atopic dermatitis (AD) is not well established.
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Patients And Methods: In this 16-week randomized-controlled trial, children aged 2-17 years with mild-to-moderate AD were enrolled.
PLoS One
January 2025
Institute of Visual Informatics, The National University of Malaysia (UKM), Bangi, Malaysia.
Patients with type 1 diabetes and their physicians have long desired a fully closed-loop artificial pancreas (AP) system that can alleviate the burden of blood glucose regulation. Although deep reinforcement learning (DRL) methods theoretically enable adaptive insulin dosing control, they face numerous challenges, including safety and training efficiency, which have hindered their clinical application. This paper proposes a safe and efficient adaptive insulin delivery controller based on DRL.
View Article and Find Full Text PDFJ Exp Zool A Ecol Integr Physiol
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Departamento de Biologia, Faculdade de Ciências, Universidade de Lisboa, Lisboa, Portugal.
The open field test (OFT) is frequently used in research to assess anxiety-like behavior and locomotor activity. Its simple design can lead to the misconception that it is a standardized procedure comparable between laboratories. However, some modifications in the setup can cause changes in behavior.
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January 2025
Department of Pediatrics and Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Background: Among hospitalized children, episodes of aggressive patient behavior place healthcare staff at risk for serious injuries. By implementing a behavioral response team at a children's hospital, we aimed to reduce monthly employee injuries related to aggressive patient behavior from 3.4 to 2.
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