Polypharmacy-the use of more medications than are clinically indicated-is a problem that affects many older adults. Adults aged 65 years and older make up approximately 13% of the population, but they consume nearly one third of all prescriptions dispensed. Older adults are more prone to adverse drug reactions and drug-drug interactions because of physiological changes and multiple comorbidities. It can be difficult to address the problem because there are many contributing factors, including multiple prescribers and specialists, the use of multiple pharmacies, and gaps in communication. The initial step is to avoid the problem. However, when this does not work, it must be identified and then treated by carefully changing medication regimens to improve the quality of care to patients. The home healthcare nurse has an essential role in this process, which will be reviewed in this article. Some of the barriers that may be encountered and examples of communication with providers are included.
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http://dx.doi.org/10.1097/NHH.0b013e31827f43b2 | DOI Listing |
Am J Geriatr Psychiatry
December 2024
Department of Gerontology, Faculty of Social Welfare & Health Sciences, University of Haifa, 199 Aba Khoushy Ave, Haifa, 3498838, Israel. Electronic address:
Objective: Unidentified sex differences in old-age cognition may emerge in psychometric networks, which look beyond mean scores into the unique cognitive structure of males and females. Accordingly, this study aims to examine cognition in well-functioning older males and females with psychometric network analysis.
Methods: The current cohort (N = 2,802) of community-dwelling adults (≥65 years) was derived from the Advanced Cognitive Training for Independent and Vital Elderly study.
J Hand Ther
January 2025
Goztepe Prof Dr Suleyman Yalcin City Hospital, Department of Neurology, İstanbul, Turkey; İstanbul Medeniyet University, Faculty of Medicine, İstanbul, Turkey.
Background: Intraneural edema is an important factor in the pathophysiology of carpal tunnel syndrome (CTS). Manual Lymphatic Drainage (MLD) is a manual treatment widely used to treat edema in a variety of conditions.
Purpose: This study aimed to evaluate the effect of MLD on intraneural edema of the median nerve in CTS patients, as well as its impact on symptom severity and hand function.
Semin Oncol Nurs
January 2025
Nursing Department, Cyprus University of Technology, Limassol, Cyprus.
Objectives: Cancer-related cachexia affects approximately 50% to 80% of cancer patients and contributes significantly to cancer-related mortality, accounting for 20% of deaths. This multifactorial syndrome is characterized by systemic inflammation, anorexia, and elevated energy expenditure, leading to severe weight loss and muscle wasting. Understanding the underlying mechanisms is critical for developing effective interventions.
View Article and Find Full Text PDFDent Mater
January 2025
Department of Oral Health Sciences, Faculty of Dentistry, The University of British Columbia, 2199 Wesbrook Mall, room 352, BC V6T-1Z3, Canada. Electronic address:
Objectives: This study aimed to assess the potential of experimental dental resins containing ZnO nanoparticles (ZnO-NPs) for antimicrobial photodynamic therapy (aPDT) as a functional tool for the modulation of cariogenic biofilm in long-term.
Methods: Minimum inhibitory and bactericidal concentrations (MIC/MBC) of ZnO-NPs against Streptococcus mutans were initially determined under different energy densities of blue LED irradiation (0.00, 1.
Zhonghua Xue Ye Xue Za Zhi
December 2024
Department of Hematology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
This study aimed to assess the efficacy and safety of gilteritinib combined with chemotherapy in treating newly diagnosed FLT3-mutated acute myeloid leukemia (AML). We retrospectively collected clinical data from 16 patients newly diagnosed with FLT3-mutated AML at Jiangsu Province Hospital. Patients received induction therapy with the classic "3 + 7" regimen or the VA regimen, and all patients were immediately supplied with gilteritinib after detecting FLT3-ITD/TKD mutations.
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