Hodgkin lymphoma transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma.

Proc (Bayl Univ Med Cent)

Section of Hematopathology. Department of Pathology, Baylor University Medical Center at Dallas, Dallas, Texas (Krause, Keglovits); and Metroplex Cancer Specialists, Keller, Texas (Drinkard).

Published: January 2013

Transformation to a large cell lymphoma may occur during the course of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) in approximately 5% of the cases. This is known as Richter's transformation. A much less frequent transformation to Hodgkin lymphoma may occur. We report a case of CLL/SLL in which a transformation to Hodgkin lymphoma occurred, and we review previously published reports of this transformation. Transformation to Hodgkin lymphoma in CLL/SLL has a poor outcome compared to de novo cases of Hodgkin lymphoma.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3523758PMC
http://dx.doi.org/10.1080/08998280.2013.11928901DOI Listing

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