A global collection of Cladophialophora carrionii strains (n = 81) was tested against nine antifungal drugs. MIC90s of all strains were as follows in increasing order: itraconazole and posaconazole, 0.063 μg/ml; terbinafine, 0.125 μg/ml; isavuconazole and voriconazole, 0.25 μg/ml; caspofungin, 2 μg/ml; micafungin, 4 μg/ml; amphotericin B, 8 μg/ml; and fluconazole, 64 μg/ml.
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http://dx.doi.org/10.1128/AAC.02114-12 | DOI Listing |
Am J Trop Med Hyg
December 2024
Department of Dermatology and Venereology, Peking University First Hospital, Beijing, China.
Chromoblastomycosis (CBM), a prevalent subcutaneous mycosis in tropical and subtropical regions caused by dematiaceous fungi, often presents as refractory lesions. This case report details a 63-year-old woman from Tianjin, China, with CBM caused by Cladophialophora carrionii after plant trauma. Successful treatment with itraconazole was performed.
View Article and Find Full Text PDFCell Mol Biol (Noisy-le-grand)
September 2024
Water Science and Environmental Engineering Research Center, College of Chemical and Environmental Engineering, Shenzhen University, Shenzhen 518060, China.
Globally, there is a growing concern about tree mortality due to harsh climates and changes in pest and disease patterns. However, experimental studies on the interactions between biotic and abiotic stresses in plants are relatively scarce. In this study, we investigated the interaction between Fusarium solani and water-stressed Dalbergia sissoo saplings.
View Article and Find Full Text PDFIMA Fungus
March 2024
Department of Medical Microbiology, The People's Hospital of Suzhou New District, Suzhou, Jiangsu, China.
Background: Chromoblastomycosis is the World Health Organization (WHO)-recognized fungal implantation disease that eventually leads to severe mutilation. Cladophialophora carrionii (C. carrionii) is one of the agents.
View Article and Find Full Text PDFJ Fungi (Basel)
July 2023
Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia 74690-900, Brazil.
Iron is a micronutrient required by almost all living organisms. Despite being essential, the availability of this metal is low in aerobic environments. Additionally, mammalian hosts evolved strategies to restrict iron from invading microorganisms.
View Article and Find Full Text PDFPLoS Negl Trop Dis
September 2022
Department of Dermatology, Hangzhou Third People's Hospital, Affiliated Hangzhou Dermatology Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Chromoblastomycosis (CBM) is a chronic fungal infection of the cutaneous and subcutaneous tissues caused by brown pigmented fungi. Fonsecaea monophora is one of the most common pathogens of CBM in China. Most formal cases have been reported from Southern China, however, the infection is not uncommon in Eastern China where very few case series are available.
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