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The association between pre-pregnancy and first-trimester hair cortisol and preterm birth: a causal inference model.
Eur J Epidemiol
December 2024
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
Adverse life events and chronic psychological distress before and during pregnancy have frequently been associated with preterm birth but the biological underpinnings remain unclear. We investigated the association between corticosteroid levels in pre-pregnancy and first-trimester hair and the risk of preterm birth. We followed N = 1,807 pregnant women from a prospective pre-birth cohort study in Lima, Perú.
View Article and Find Full Text PDFImpact of repeated intranasal gentamicin irrigation on auditory brainstem evoked potentials in rats.
Exp Brain Res
December 2024
Department of Anatomy, Lake Erie College of Osteopathic Medicine, 1858 West Grandview Blvd Erie, Erie, PA, 16504, USA.
Gentamicin is a bactericidal aminoglycoside antibiotic that broadly targets Gram-negative microbes. Both human and animal studies have shown that administration of gentamicin is ototoxic by several routes of administration and results in sensorineural hearing loss due to damaged hair cell at the base of the cochlea. However, gentamicin is also administered intranasally to treat sinusitis in humans, but no animal studies have examined ototoxicity of gentamicin administered via this route.
View Article and Find Full Text PDFIntroduction: The teratogenic effect of alcohol is well known, but its prevalence is usually underestimated. This study presents the findings of a cross-sectional study conducted in Poland, which aimed to assess the prevalence and changes in alcohol consumption during pregnancy. The study utilized ethyl glucuronide concentration in maternal hair and self-reports as measures to evaluate alcohol intake across the three trimesters of pregnancy.
View Article and Find Full Text PDFHearing loss in newborn infants with hypoxic ischaemic encephalopathy: protocol for a case-control study.
BMJ Paediatr Open
November 2024
Neonatal Unit, Homerton Healthcare NHS Foundation Trust, London, UK
Introduction: Hypoxic ischaemic encephalopathy (HIE), a condition where the brain does not receive enough oxygen and/or blood flow around the time of birth, is associated with significant morbidity and mortality. Systemic circulation may be affected due to poor myocardial function. The cochlear hair cells are vulnerable to changes in microcirculation, which may occur in HIE predisposing to hearing loss.
View Article and Find Full Text PDFThe use of cosmetics, personal care and cleaning products during pregnancy: a cross-sectional study.
Int J Environ Health Res
November 2024
Faculty of Health Sciences, Department of Nursing, Giresun University, Giresun, Türkiye.
This study was planned to determine the use of cosmetics, personal care and cleaning products containing chemicals during pregnancy and the affecting factors. The study is quantitative, descriptive and cross-sectional. The sample size was calculated using the G*Power program.
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