Effect of HIV on liver fibrosis among HCV-infected African Americans.

Clin Infect Dis

Critical Care MedicineDepartment, National Institutes of Health, 1101 Highland Dr, Silver Spring, MD 20910, USA.

Published: May 2013

Degree of liver fibrosis largely determines treatment urgency for hepatitis C virus (HCV). This retrospective study examined fibrosis stages and predictive factors in African Americans with HCV monoinfection and human immunodeficiency virus (HIV)/HCV coinfection. Nearly 50% of patients had early-stage fibrosis in the study, despite the long duration of infection in many patients. HIV was associated with the early fibrosis group. These results indicate that a large proportion of patients with HCV infection, including those with HIV, could possibly await more-effective and better-tolerated treatment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657492PMC
http://dx.doi.org/10.1093/cid/cit037DOI Listing

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