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Dexmedetomidine in colon cancer surgery: Evaluating its impact and efficacy.
World J Gastrointest Surg
December 2024
Department of Anaesthesiology, All India Institute of Medical Sciences, Bathinda 151001, India.
We present an editorial on an article that highlights the benefits of dexmedetomidine (Dex) in colon cancer surgeries, which have been thoroughly investigated in the referenced publication involving 117 subjects. Of these patients, 59 (group A) received Dex before anesthesia induction, while 58 (group B) received normal saline. Group A patients demonstrated several advantages over Group B, including lower propofol and remifentanil requirements, improved cerebral oxygenation as measured by regional cerebral oxygen saturation, better hemodynamic stability, and reduced incidence of postoperative cognitive dysfunction.
View Article and Find Full Text PDFComparison of the effects of remimazolam and dexmedetomidine on the quality of recovery in functional endoscopic sinus surgery: a randomized clinical trial.
BMC Anesthesiol
December 2024
Department of Anesthesiology, Anqing Medical Center of Anhui Medical University, the Fifth Clinical Medical School of Anhui Medical University, No.87 Tianzhushan East Road, Anqing, 246003, Anhui, China.
Background: Postoperative pain usually occur in patients who have undergone functional endoscopic sinus surgery (FESS). Remimazolam and dexmedetomidine could enhance the quality of recovery (QoR) after surgery. The aim of this study was to compare the effects of remimazolam and dexmedetomidine with respect to the QoR-40 score of patients who have undergone FESS.
View Article and Find Full Text PDFImpact of Dexmedetomidine-Based Opioid-Sparing Anesthesia on Opioid Use After Minimally Invasive Repair of Pectus Excavatum: A Prospective Randomized Controlled Trial.
J Clin Med
November 2024
Department of Anesthesiology and Pain Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Opioid-sparing anesthesia (OSA) using dexmedetomidine has gained attention as an alternative to opioid-based anesthesia (OBA) due to its potential to reduce opioid consumption and the associated side effects. This study aimed to investigate the effect of dexmedetomidine-based OSA on postoperative pain intensity, opioid consumption, and recovery outcomes in patients undergoing a minimally invasive repair of pectus excavatum. Eighty-four patients undergoing a minimally invasive repair of pectus excavatum were randomized to either the OSA group, receiving dexmedetomidine, or the OBA group, receiving remifentanil.
View Article and Find Full Text PDFLongitudinal Trends in the Incidence of Hyperactive Delirium and Its Causes of Change After Surgery for Degenerative Lumbar Disease: A Population-Based Study of 7250 Surgical Patients Over 11 Years.
Orthop Surg
December 2024
Orthopedic Hospital, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Article Synopsis
- The study investigates the occurrence and causes of hyper-postoperative delirium in elderly patients undergoing spinal surgery for lumbar degenerative diseases over an 11-year period, as severe delirium can lead to serious complications.
- It includes a retrospective review of 7,250 patients from 2011 to 2021, diagnosing cases of delirium using recognized assessment methods and categorizing the incidence trends into three distinct periods.
- The overall incidence of hyper-postoperative delirium was found to be 1.79%, with a patient average age of 54.5 years, and the study aims to determine factors influencing these trends through statistical analyses.
Pharmacological interventions for remifentanil-induced hyperalgesia: A systematic review and network meta-analysis of preclinical trials.
PLoS One
December 2024
Institute of Applied Health Sciences, Epidemiology Group, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, United Kingdom.
Background: To improve perioperative pain management, several interventions have been suggested for the prevention of increased pain sensitivity caused by opioids (called opioid-induced hyperalgesia). It is currently unclear which intervention is the most effective or appropriate in preventing opioid-induced hyperalgesia. Remifentanil is the most investigated opioid causing opioid-induced hyperalgesia.
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