Objective: To examine the feasibility and efficacy of a modified constraint induced therapy protocol on stroke patients.
Methods: This study was carried out during the period from August 2001 to January 2002 at the Riyadh Medical Complex, Riyadh, Kingdom of Saudi Arabia. Six stroke patients with subacute cerebrovascular accident (<6 months) were included in the study. Three male and 3 female patients with a mean age of 54.3+/-6.9 years (range 45-67 years), and mean duration of hemiparesis of 4.7 months (range 2.3-5.8 months). They were divided randomly into 3 groups of 2 patients. The first 2 patients (constraint induced therapy group) participated in half an hour of physical and occupational therapy sessions 3 times per week for 10 weeks. During the same period, their unaffected arms and hands were restrained 5 days per week for 5 hours identified as times of frequent use. The second 2 patients (traditional therapy group) received regular therapy administered after 10 weeks. The last 2 patients (control group) received no therapy. The Fugl-Meyer Assessment of Motor Recovery After Stroke (Fugl), Action Research Arm Test (ARA), Wolf Motor Function Test (WMFT), and Motor Activity Log (MAL) were administered to the patients.
Results: Patients receiving modified constraint induced therapy exhibited substantial improvement on the Fugl, ARA, and WMFT, as well as increases in amount and quality of use of the limb using the MAL. While patients receiving traditional physical and occupational therapy, and no therapy patients exhibited few improvements.
Conclusion: Modified constraint induced therapy may be an efficacious method of improving function and use of the affected arms in stroke patients exhibiting learned nonuse.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Recent advances in fucoidan-based improved delivery systems: Structure, carrier types and biomedical applications.
Carbohydr Polym
March 2025
Key Laboratory of Dairy Science, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin 150030, China; Key Laboratory of Infant Formula Food, State Administration for Market Regulation, Harbin 150030, China. Electronic address:
Consumer demand for nutritional supplements has fueled the rapid growth of the functional food market. However, ensuring the stability of functional factors in harsh environments remains a major challenge. The development of encapsulation systems is regarded as an effective method for enhancing the stability of functional factors, encapsulation carriers can offer protection for these functional factors.
View Article and Find Full Text PDFTofacitinib in focus: Fascinating voyage from conventional formulations to novel delivery systems.
Int J Pharm
January 2025
Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKMs NMIMS, V.L. Mehta Road, Vile Parle (W), Mumbai, Maharashtra 400056, India. Electronic address:
Tofacitinib, a Janus kinase (JAK) inhibitor, has emerged as a primary therapeutic agent for managing autoimmune diseases such as rheumatoid arthritis, psoriatic arthritis, dermatitis and ulcerative colitis. By inhibiting the phosphorylation of JAK enzymes, tofacitinib prevents their activation within the JAK-STAT signaling pathway, which is vital for inflammatory responses. However, the tofacitinib delivery presents significant challenges, including pH-dependent solubility, poor permeability and susceptibility to oral degradation.
View Article and Find Full Text PDFStress-enhanced fear learning can be reduced with unconditional stimulus deflation with constraints.
Behav Brain Res
January 2025
Department of Psychological and Brain Sciences, Indiana University, USA. Electronic address:
Exposure to extreme stress can negatively impact behavior and lead to prolonged fear sensitization. These processes can be studied in the lab using stress-enhanced fear learning (SEFL), where prior exposure to inescapable stress exacerbates later contextual fear conditioning. A common method to reduce conditional fear is through extinction, where a conditional stimulus once paired with an unconditional (US; e.
View Article and Find Full Text PDFAdult-type ALCAPA: missed at preoperative evaluation.
Indian J Thorac Cardiovasc Surg
February 2025
Ankara City Hospital Cardiovascular Surgery, Ankara, Turkey.
Unlabelled: The Bland-White-Garland syndrome, or Anomalous Origin of the Left Coronary Artery from the Pulmonary Artery (ALCAPA) syndrome, is a rare congenital cardiac anomaly often associated with high mortality, if left untreated. We present a case of a 43-year-old female with undiagnosed ALCAPA who initially underwent mitral valve surgery for severe mitral regurgitation, only to require reoperation due to adult-type ALCAPA. Intraoperatively, the discovery of dilated right coronary artery and its branches and absence of the left coronary ostium prompted further investigation, leading to the diagnosis of adult-type ALCAPA.
View Article and Find Full Text PDFDeep Learning for Predicting Difficulty in Radical Prostatectomy: A Novel Evaluation Scheme.
Urology
January 2025
Department of Urology, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China; Institute of Urologic Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei, 430060, China. Electronic address:
Objectives: To explore new metrics for assessing radical prostatectomy difficulty through a two-stage deep learning method from preoperative magnetic resonance imaging.
Methods: The procedure and metrics were validated through 290 patients consisting of laparoscopic and robot-assisted radical prostatectomy procedures from two real cohorts. The nnUNet_v2 adaptive model was trained to perform accurate segmentation of the prostate and pelvis.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!