The effect of estrone injections on heterotopic marrow organ formation and femoral hemopoiesis and osteogenesis was studied in C57B1 X CBAF1 mice. Estrone injections resulted in decreased hemopoiesis in femoral marrow, its fibrosis and reduced cellularity of heterotopic organ. Any correlations between osteogenic and hematopoietic tissue were not revealed.
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