Importance of protein dynamics during enzymatic C-H bond cleavage catalysis.

Biochemistry

Department of Chemistry, Department of Molecular and Cell Biology, and California Institute for Quantitative Biosciences (QB3), University of California, Berkeley, California 94720-3220, United States.

Published: March 2013

Quantum tunneling and protein dynamics have emerged as important components of enzyme function. This review focuses on soybean lipoxygenase-1, to illustrate how the properties of enzymatic C-H bond activation link protein motions to the fundamental bond making-breaking processes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091948PMC
http://dx.doi.org/10.1021/bi301504mDOI Listing

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