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Blood flow restriction-enhanced platelet-rich plasma: A pilot randomised controlled trial protocol.
J Exp Orthop
January 2025
Centro Médico Profesional Las Mercedes, Av. Principal de Las Mercedes Caracas Venezuela.
Purpose: To assess platelet-rich plasma (PRP) changes in platelet and leucocyte count, insulin-like growth factor 1 (IGF-1), and interleukin 6 (IL-6) concentration after bilateral low-load knee extensions under blood flow restriction (BFR).
Methods: The present randomised controlled trial protocol will include two groups: the intervention group, which will undergo bilateral knee extensions under BFR, and the control group, which will perform bilateral knee extensions without BFR. Participants will be randomly allocated in a 1:1 ratio.
Leg Blood Flow During Exercise with Blood Flow Restriction: Evidence for and Implications of Compensatory Cardiovascular Mechanisms.
J Appl Physiol (1985)
January 2025
School of Kinesiology and Health Studies, Queen's University, Kingston, Ontario, Canada.
Proximal limb cuff inflation to 40% arterial occlusion pressure (AOP) is assumed to reduce exercising leg perfusion, creating "blood flow restriction" (BFR). However, no study has validated this assumption. 18 healthy young participants (9F) performed two-legged knee flexion/extension exercise at 25% WRpeak with bilateral cuffs applied to the proximal thigh at 0% AOP (CTL), 20% AOP and 40% AOP.
View Article and Find Full Text PDFExperiences of receiving formal psychological support following lower limb amputation: a qualitative study.
Disabil Rehabil
January 2025
School of Health and Medicine, Lancaster University, Lancaster, United Kingdom.
Purpose: This study sought to explore the experiences of receiving formal psychological support following non-vascular-related lower limb amputation.
Materials And Methods: Semi-structured interviews were conducted with five individuals (3 males, 2 females, aged 38-56) with lower limb loss. Two had unilateral above knee amputations, one a unilateral below knee amputation, one a unilateral through-knee amputation, and one had bilateral above knee amputations.
Tourniquet and/or Adductor Canal Block Use Confer No Additional Early Quadriceps Weakness Following Total Knee Arthroplasty: An Analysis of 203 Patients.
Iowa Orthop J
January 2025
Department of Orthopedic Surgery, NYU Langone Health, New York, New York, USA.
Background: Quadriceps weakness following total knee arthroplasty (TKA) delays rehabilitation and increases fall risk. The combined impact of tourniquets and adductor canal blocks (ACBs) on postoperative quadriceps strength has not been defined. This study evaluated the early effects of tourniquet and/or ACB usage on quadriceps strength following TKA.
View Article and Find Full Text PDFLimb Underloading in Walking Transmits Less Dynamic Knee Joint Contact Forces after Anterior Cruciate Ligament Reconstruction.
Med Sci Sports Exerc
November 2024
Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC.
Introduction: Individuals with anterior cruciate ligament reconstruction (ACLR) often walk with a less dynamic vertical ground reaction force (vGRF), exemplified by a reduced first peak vGRF and elevated midstance vGRF compared to uninjured controls. However, the mechanism by which altered limb loading affects actual tibial plateau contact forces during walking remains unclear.
Methods: Our purpose was to use musculoskeletal simulation to evaluate the effects of first peak vertical ground reaction force (vGRF) biofeedback on bilateral tibiofemoral contact forces relevant to the development of post-traumatic osteoarthritis (OA) in 20 individuals with ACLR.
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