In this study, RipSeq Mixed, a software resolving uninterpretable mixed DNA sequencing chromatograms, revealed the bacterial content of 15 polymicrobial samples. Direct sequencing combined with RipSeq Mixed constitutes a valuable supplement to cultivation, particularly when cultivation is negative and direct sequencing is inconclusive despite continued clinical indications of infection.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666778 | PMC |
| http://dx.doi.org/10.1128/JCM.00190-13 | DOI Listing |
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