New alkylated benzoquinone from Iris nepalensis.

Nat Prod Res

a National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, MS 38677 , USA.

Published: October 2013

Chemical investigation of chloroform extract of rhizomes of Iris nepalensis yielded new alkylated 1,4-benzoquinone derivative (1). The structure of Compound 1 was established by analysis of spectroscopic data. Compound 1 was evaluated for cytotoxic activities against human cancer cell lines A549, HL-60, HCT116 and ZR-75. Compound 1 showed least cytotoxicity against HL-60, HCT116 and ZR-75-30.

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http://dx.doi.org/10.1080/14786419.2012.763124DOI Listing

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