AI Article Synopsis
- The methanol extract from Salacia hainanensis roots led to the discovery of three new compounds along with six known triterpenoids.
- The structures of these compounds were determined using advanced techniques like two-dimensional NMR and high-resolution mass spectrometry.
- Some of the new compounds exhibited significantly stronger inhibitory activity against α-glucosidase compared to the standard drug acarbose.
Article Abstract
The methanol extract from roots of Salacia hainanensis Chun et How afforded three new compounds, 24,26-dihydroxy-25-methoxy-tirucall-9-en-3-one (1), 2β,3β,22α-trihydroxy-lup-20(29)-ene (2) and 3β-hydroxy-2-carbonyl-lupan-29-oic acid (3), along with six known triterpenoids (4-9). Their structures were established on the basis of spectral analysis, in particular according to the data obtained by two-dimensional-NMR and high-resolution mass spectra experiments. Some of them showed much stronger inhibitory activity towards α-glucosidase than the positive control (acarbose, IC₅₀ 10.2 μM).
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| http://dx.doi.org/10.1007/s11418-013-0744-5 | DOI Listing |
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