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Cost-effectiveness analysis of radiofrequency renal denervation for uncontrolled hypertension in Canada.
J Med Econ
December 2025
Wing Tech Inc., Menlo Park, California, USA.
Aims: Catheter-based radiofrequency renal denervation (RF RDN) is an interventional treatment for uncontrolled hypertension. This analysis explored the therapy's lifetime cost-effectiveness in a Canadian healthcare setting.
Materials And Methods: A decision-analytic Markov model was used to project health events, costs, and quality-adjusted life years over a lifetime horizon.
An International Consensus Practical Guide on Left Atrial Appendage Closure for the Non-implanting Physician: Executive Summary.
Thromb Haemost
December 2024
St. George's University of London, London, United Kingdom.
Article Synopsis
- Many patients with atrial fibrillation (AF) are not receiving or are stopping oral anticoagulation therapy, despite its importance for stroke prevention.
- While direct oral anticoagulants (DOACs) are available, issues like bleeding risks, poor compliance, and aversion to treatment contribute to this problem.
- A recent expert consensus guide highlights left atrial appendage closure (LAAC) as a safe alternative for stroke prevention in patients who cannot use long-term anticoagulation, detailing the devices, implantation technique, and follow-up requirements for non-implanting physicians.
Prevalence and Center Variability of Catheter-Based Hemodialysis in Vienna: Insights from the Vienna ACTS NOW Study.
J Clin Med
November 2024
Department of Vascular Surgery, Clinic Ottakring, 1160 Vienna, Austria.
Article Synopsis
- The study focuses on the use of central venous catheters (CVCs) in chronic hemodialysis patients in Vienna, noting that this practice is still common despite the preference for arteriovenous (AV) fistulas.
- A cross-sectional analysis of 335 CVC-based hemodialysis patients revealed a 42.5% prevalence of CVC use, with most patients eligible for either AV fistula or graft creation.
- The findings suggest that improving access to in-house vascular surgery could reduce reliance on CVCs and associated complications in hemodialysis patients in Vienna.
Catheter-Based Renal Denervation for Resistant Arterial Hypertension: 10-Year Real-World Follow-Up Data.
J Clin Hypertens (Greenwich)
December 2024
Department of Cardiology, Cardiovascular Center Aalst, Aalst, Belgium.
This analysis of real-world data examines the efficacy, safety, and long-term outcomes of renal denervation in hypertensive patients for up to 10 years. Sixty-five consecutive patients underwent renal denervation (RDN) (single operator) for uncontrolled resistant hypertension. Efficacy was defined as the interindividual change of office (OBPM) and ambulatory blood pressure monitoring (ABPM) at 1, 6, 12 months, 2-4 and 5-10 years after RDN.
View Article and Find Full Text PDFCatheter-Based Radiofrequency Renal Denervation in the United States: A Cost-Effectiveness Analysis Based on Contemporary Evidence.
J Soc Cardiovasc Angiogr Interv
October 2024
Wing Tech Inc, Menlo Park, California.
Background: Catheter-based radiofrequency renal denervation (RF RDN) has recently been approved as an adjunctive treatment for hypertensive patients without adequate blood pressure control. This study assessed the cost-effectiveness of RF RDN in the United States based on contemporary clinical evidence.
Methods: A decision-analytic Markov model projected costs, quality-adjusted life years (QALY), and clinical events for an active cohort treated with RF RDN and a control cohort treated with standard-of-care (defined as 1, 2, or 3 antihypertensive medications).
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