pH dependent multifunctional and multiply-configurable logic gate systems based on small molecule G-quadruplex DNA recognition.

Chem Commun (Camb)

Department of Organic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata-700032, India.

Published: March 2013

A variety of logic operations such as XNOR, NOR, AND, NAND, NOT have been designed with pH as an external modulator by choosing thiazole orange (TO) and a c-kit2 promoter quadruplex as two inputs and fluorescence signals of pyridyl bis-indole amide (PBIA) and TO as two outputs.

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http://dx.doi.org/10.1039/c3cc38888cDOI Listing

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