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| http://dx.doi.org/10.5811/westjem.2012.6.12680 | DOI Listing |
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Deterioration of preexisting myoclonus following nifedipine use in parkinsonian syndrome: A case report.
eNeurologicalSci
March 2025
Department of Neurology, Nagoya City University Graduate School of Medical Sciences, Aichi, Japan.
L-type calcium channel antagonists are uncommon causes of myoclonus, and the underlying mechanism remains unclear. Here, we report a case of parkinsonian syndrome with deterioration of preexisting myoclonus after nifedipine use. A 96-year-old woman was administered a single dose of sustained-release nifedipine for chest pain.
View Article and Find Full Text PDFBackground: Based on preclinical data showing addition of CDK4/6 inhibitors to gemcitabine was synergistic, ribociclib was evaluated in combination with gemcitabine to determine the maximum tolerated dose (MTD) and dose limiting toxicities (DLT).
Methods: In this single arm multicohort phase I trial, we evaluated the safety and efficacy of ribociclib plus gemcitabine in patients with advanced solid tumors. Patients received gemcitabine intravenously on days 1 and 8 followed by ribociclib days 8-14, with treatment repeated every 3 weeks.
A physiotherapeutic approach to a baby with right disgenesis of thumb and left agenesis of upper extremity: A case report.
Prosthet Orthot Int
January 2025
Ida Orthopedics, Istanbul, Turkey.
A boy with bilateral congenital anomalies of the upper extremities with transverse absence of the left arm (agenesis) and absence of right thumb (disgenesis), fixed elbow in extension due to humeroradial synostosis thought that the humerus was intact. His wrist could move passively with 50° flexion, 0° extension, and 70° radial deviation. The other 4 fingers were intact, 4-5 metatarsal bones were in synostosis, and the fifth finger was clinodactyly.
View Article and Find Full Text PDFContinuous Costoclavicular Brachial Plexus Block for Humeral Fractures in Pregnancy: A Case Report and Literature Review.
J Perianesth Nurs
January 2025
Department of Anesthesiology, Ningbo No.6 Hospital, Ningbo University School of Medicine, Ningbo, Zhejiang, China. Electronic address:
Brachial plexus block is the predominant anesthetic method used for upper-limb surgical procedures in pregnant patients. The innovative method of brachial plexus block in the costoclavicular space has shown enhanced reliability and effectiveness for postoperative analgesia. We report a case of a pregnant woman who underwent surgery for a humeral fracture.
View Article and Find Full Text PDFEfficacy of solution-focused brief therapy versus case management for psychological distress in adolescents and young adults in a community-based youth mental health service in Singapore: protocol for a randomised controlled trial.
BMJ Open
December 2024
North Region and Department of Psychosis, Institute of Mental Health, Singapore.
Introduction: There are insufficient scalable, evidence-based treatments to meet increasing mental health needs of young people. Offering interim, brief interventions for young persons with psychological distress can improve access to care and mitigate adverse effects of long waiting times. This study tests the efficacy of solution-focused brief therapy (SFBT), a strength-based, goal-directed intervention, in adolescents and young adults at a community-based youth mental health service in Singapore.
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